Alpha amylase is elevated in the blood. The reasons that this means the treatment in adults and children

Blood biochemical indicators give a complete picture of overall health. An item such as alpha amylase, increased blood for several reasons related to the functional activity of the stomach and salivary glands. Elevated levels of the enzyme indicates pancreatitis.

What is alpha amylase

The term derives from the Greek «μυλον» - «starch". Its purpose in the human body - the conversion of starch to oligosaccharides during the digestion of carbohydrate components of food. The enzyme was first studied in digestion substance when Professor Anselme Payen in 1833 presented a description diastase.

This combination of elements to break down starch into maltose. Under the influence of alpha amylase and appears sweet taste during prolonged chewing of starchy foods. Pancreas itself on 90% consists of acinar tissue that distinguishes pancreatic juice. Its structure and include amylase, lipase and proteolytic enzymes in the inactivated form.

Amylase is intended for the breakdown of carbohydrates. Lipase - a water-soluble enzyme for hydrolysis of water-insoluble fat and lipid substrates.

Pancreatic juice flows into a central duct, further mixed with concentrated in bile-pancreatic and hepatic capsule. For the isolation of the resulting fluid in the duodenum 12 meets the sphincter of Oddi. In healthy pancreatic protease activated in the small intestine. They were then the action begins in the digestive tract of man.

But after physical damage during or after occlusion of the ducts use of alcoholic beverages injured tissue, inflamed and swollen. Partitions acinar areas become too permeable.

As a result, pancreatic substances penetrate through the vessel wall and are mixed with blood, thus deforming itself pancreas. This condition is dangerous to health. It is unacceptable to ignore the symptoms of the disease. It is necessary as soon as possible to contact the experts dealing with the problems of the digestive tract.

norms

Normal performance does not depend on the gender of the person, and by the age of 2 years is achieved stable values.

Age	Norm u / l
Up to 2 years	5-65
From 2 to 70 years	25-100
More than 70 years	30-160

Alpha amylase in the blood increases when the menopause due to significant changes in hormonal levels. The condition is not related to the pathological and does not require correction.

high scores

Alpha amylase increased blood: the reasons for this condition may be caused by systemic diseases and pathologies of the internal organs:

• pancreatitis - inflammation of the pancreatic tissue, wherein the indicators are significantly increased;
• diabetes - a violation of the process of digestion of carbohydrates, amylase is not spent properly and gradually accumulate;
• Mumps or mumpsIt leads to marked inflammatory process salivary glands, one function of which - the secretion of alpha amylase;
• kidney failure - enzymes are secreted by the kidneys with the secreted urine in kidney dysfunction amylase content increases.

Among the symptoms are present epigastric pain, often immediately after a meal. There is a general malaise, weakness, loose stools. Pain associated with disorders of the pancreas, have a bright expression. At elevated levels of digestive organ tissue substances are gradually destroyed. Developing pancreatitis.

At advanced stages of the disease may develop pancreatic necrosis - a gradual withering away of pancreatic tissue.

State refers to deadly, and therefore requires immediate treatment. After the first episode of pancreatitis should be careful in choosing food. And when using greasy or indigestible food take enzymes for the prevention of exacerbations of chronic gastrointestinal diseases.

low rates

Alpha amylase is elevated in the blood: Causes of this condition in children are related to the fact that breast milk does not contain carbohydrates that require splitting. Therefore, low rates are the norm. However, as the inflated values ​​of alpha amylase, and an insufficient level of an adult, requires a deeper examination.

The reasons for poor performance:

• hepatitis - liver pathology, in which there is an infringement of its functions, abnormal absorption of nutrients and carbohydrates;
• tumors in the pancreas are the cause of the degeneration of its tissue and impaired production of enzymes.

Also, the state is observed in intestinal obstruction and inflammation of the appendix. These diseases require emergency surgery to save the life of the patient. The danger of inflammation of appendicitis is primarily associated with the probability of it breaking and entering content into the abdominal cavity. Against this background, may develop peritonitis.

serious intervention for intestinal lavage, and receive powerful antibiotics to restore the health of the victim is required. And the incision in the abdomen accompanied by the need to cut the muscle layer.

Full recovery after this should be expected. Plus unpleasant cosmetic defect in the form of rough scar on the abdomen, which is able to reduce only very expensive and prolonged treatment with special gel type Kontraktubeks.

Effects

Expressed change parameters to increase with time lead to pancreatic lesion, gastrointestinal tract, liver. A significant deterioration in the patient's state of health would indicate severe organ deformation.

In order to restore functional activity of preparations required for liver and gastrointestinal based PUFAs essential phospholipids, pancreatin and other biologically active substances. The sharp decline in performance will be accompanied by defective digestion of carbohydrates, insufficient levels of glucose in the blood plasma, deficiency of energy and calories.

It is therefore very important to find out the exact cause of the low level of alpha amylase. Modern equipment in clinics allows to objectively evaluate the function of all body systems. An experienced physician on the basis of the data obtained will determine the cause and prescribe the best treatment.

When the prescribed tests

The reason for the examination body will pain in the stomach, the liver, disturbances of the chair and the total human weakness, in which the appetite disappears, there is a body weight loss and lead to abnormalities digestion. For a complete picture of determining the content of alpha amylase in urine and blood.

Fence for biomaterial studies carried out from a vein. Capillary blood does not give correct results. After the primary sampling control assays required to monitor the body's response to drugs are taken. The frequency of these procedures determined by a physician.

And only after a complete normalization of the survey can be stopped. For the prevention of relapse and early detection of other serious diseases it is recommended to take biomaterials full range of biochemical parameters at least 1 time per year.

How to prepare for analysis

Biochemical blood analysis provides a complete view of the status and health of the person. An indicator such as alpha amylase, is increased in the blood for a variety of reasons related to the functional activity of the pancreas. Blood sampling is carried out in the morning on an empty stomach. Therefore, eating breakfast and drinking sweetened beverages is prohibited on the appointed day.

One day before the analysis can not take fatty, spicy foods with a high content of carbohydrates (bread, rice, pasta, sweets, and sugar). It is recommended to limit the consumption of coffee, tea and sodas. On the eve of the analysis to avoid stress and physical overexertion.

It is also undesirable to drink a lot, so as not to dilute the liquid blood and not to provoke excessive excretion of alpha amylase in urine. In order not to overdo it to the fence biomaterials, better to prefer a taxi instead of public transport if there is no personal car.

As the analysis

Blood sampling was performed using volumetric syringe from a vein in the elbow. Before taking biomaterial should actively work brush to activate blood circulation and vein filling itself. During the intake cam to be compressed.

Immediately after withdrawal of the needle must puncture firmly pressed region prospirtovannym swab elbow bend and remain in that position for at least 5 min.

The last recommendation is the fact that the needles used for the abstraction of biomaterials thicker than for intravenous drips. Therefore, the blood longer and more abundant stands out from the vein into the surrounding tissue. Neglecting this condition will lead to the formation of extensive bruising and prolonged resorption.

Should avoid the bruising was not possible, you can use an ointment type finalgon with an extract of red pepper. As well removes bruises all known Vietnamese asterisk. Essential oils in its composition penetrate human skin, increase blood flow, cool and soothe the skin.

How to normalize the indicator

Alpha amylase is elevated in the blood: Causes of this condition can be eliminated with the help of medical devices. Among specific drugs exist and Contrycal Gordoks. Contrycal - polypeptide derived their lung tissue of cattle. Substance turns off the kallikrein-kinin system. It reduces the overall proteolytic activity of enzymes.

It is produced as a lyophilisate for mixing a solution for intravenous administration. 1 pack contains 10 flasks with lyophilized and the vials 10 with the solvent.

Gordoks - preparation on the basis of aprotinin. The substance also inhibits proteolytic activity. It leads to the formation of stoichiometric complexes reversible blocking activity of tissue and plasma kallikrein, plasmin and trypsin.

It is used in surgery to reduce blood loss and need for transfusion. 1 vial contains 100,000 KIU of aprotinin. Available in packs of 5 or 25 pieces.

If the access to professional help for the administration of drugs is not, we can restrict the reception of digestive enzymes pancreatin - Mezim, Creon, and others. Compensation of pancreatic activity will give her the opportunity for self-recovery. Preparations are made strictly during the meal.

During the course of treatment will require regular monitoring of blood dynamics. The frequency of sampling biomaterials determine gastroenterologist after treatment. And the most important rule - a complete rejection of the use of alcohol. Ethanol - is a powerful toxic agent for pancreatic cancer.

The strongest negative effect is observed when used on an empty stomach in large quantities and on a regular basis. During acute pancreatitis pain is very intense, eating is even stronger urgency. To facilitate the initial condition of the patient is allowed to take enzymes, regardless of the meal.

After the start of relief should slowly begin to eat light food without fat and fiber content: cereals, dairy products and frayed cottage cheese, lean meat or chicken boiled. You can then enter the normal white bread. And be sure to continue to take enzymes. Smooth approach will quite quickly remove the aggravation and restore pancreatic function in full.

Changing the alpha amylase norm in children

The pancreas in children, as well as other internal organs are not actively functioning. Over the years it matures, and digestion to normal. Precipitating factor is the use of excessive amounts of sweet, carbonated beverage, the propensity to bite or gap length between meals.

In order to prevent or get rid of existing violations in the pancreas, to be observed eating regime to eliminate all harmful and avoid snacking. The menu must be based soups of meat, vegetables and cereals. Mayonnaise, ketchup and other sauces should be completely excluded, especially if it is already marked by the negative symptoms of pancreatic.

Alpha amylase increased Blood: causes can be eliminated by performing simple rules. In order to reduce the burden on the digestive tract of the child, it is recommended to grind the food puree using a blender or kitchen masher.

Young child should feed a teaspoon, older children reminded to chew food, abundantly wetting with saliva. You can not overfeed the child for the normalization of the state of health. Fractional meals throughout the day will lead to the digestion and facilitate the functioning of internal organs. If there are problems with pancreas suitable capsule Creon.

Their contents look like little balls. Problems with swallowing will occur. It is only right to give the drug to wash down with a little water, not allowing a child to crack granules.

Against the background of inflammation of the pancreas meal is very difficult. Due to malnutrition, and hypersecretion of enzymes for digestion may develop gastritis or exacerbation of existing chronic form. A very effective means is natural honey.

To purchase a natural product, it is best to contact an honest beekeepers. Among acquaintances surely there is someone who can provide a reliable contact person. The only condition for a successful outcome of this therapy - a reception in small portions, alternating with tea or water.

Most importantly, remember that honey can not tolerate heat. Therefore, mix it with hot tea can not. Failure to comply with this rule can cause the emission of carcinogenic substances, and all the benefits disappear.

Elevated levels of alpha amylase in the blood can and should be corrected.

Values ​​below reference talk about the reasons associated with the defective functioning of the liver, thyroid or pancreas. In adolescents and in young children is too low figures suggest possible genetic pathologies such as cystic fibrosis, and other fermentopathy. Therefore, early treatment is essential for normal development in the future.

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