Troxerutin. Instructions for use, for which the ointment / gel / capsules / tablets. Price, reviews, analogues

Troxerutin - pharmacological drug used in treatment of chronic venous insufficiency forms. According to the instructions for use, it is venous drug.

issuance

Troxerutin produced in 2 dosage forms - gel capsule and enteric.

Gel

The gel is applied topically. The level of active ingredients - 2%. Uniform consistency from light yellow to light brown color. Produced in glass bottles or aluminum tubes, packed in cardboard container. Cost - from 22 to 274 rubles. of means, depending on the dosage.

Indications following gel:

• various forms of thrombophlebitis;
• trophic ulcers that develop during circulatory disorders;
• varicose veins including edema;
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• bruising;
• calf cramp at night;
• form varicose dermatitis;
• the formation of post-traumatic edema.

capsules

The capsules are yellow. Inside each tablet granular powder. Packaged pills in plastic blister with 10, 15 and 20 pieces. Also means packaged in polymeric containers. Cost - from 45 up to 1166 rubles. depending on the dosage.

Indications for use of capsules:

• elimination of the symptoms of hemorrhoids;
• trophic disorders caused by chronic venous insufficiency of the course;
• the consequences and complications of thrombotic diseases;
• the postoperative period;
• periflebit;
• hemorrhagic diathesis form;
• kapillyarotoksikoz;
• various forms of diabetes and complications - retinopathy, angiopathy.

Medication is effective in personal injury and damage - bruises, sprains, torn tendons.

Structure

The preparation is applied only after established form of the disease.

The main active ingredient of the drug is troxerutin.

Additional components (Gel):

• 0.7 mg of sodium hydroxide 30% solution;
• 0.6 mg carbomer 940;
• 0.0575 mg of benzalkonium chloride;
• 0.05 mg of disodium edetate;
• filtered water.

Auxiliary components (for capsules):

• 44.1 mg of microcrystalline cellulose;
• 9.25 mg of talc;
• 9.25 mg sodium carboxymethyl starch;
• 3.7 mg of povidone.

Sheath each dragee consists of iron oxide, titanium dioxide and gelatin.

Farmodinamika

Medication belongs to a group of semisynthetic bioflavonoids. P exhibits activity has angioprotective, venotonic effect. Pharmaceutical remedies eliminate edema, relieves inflammatory responses and promotes vascular permeability reducing capillaries.

Active ingredient inhibits the action of hyaluronidase involved in redox processes. In this case, the main ingredient of hyaluronic acid restores the balance, reduces capillary permeability membranes.

The main substance exhibits antioxidant effect, reduces the risk factors and lipid oxidation processes, ascorbic acid. The mechanism of action caused by high inhibitory properties of the drug preventing the development of capillary permeability and fragility.

The drug is aimed at increasing the density of the vessel walls, which reduces the factors contributing to the output of corpuscles through the walls of veins and capillaries. This is accompanied by elimination of inflammation, platelet aggregation observed decline.

Application tool eliminates the symptoms associated with the development of venous insufficiency, helping to reduce swelling and improve the trophic tissue.

Pharmacokinetics

Troxerutin, instructions for use which indicates a high absorbency drug when administered orally is well absorbed and rapidly inside. The plasma concentration of the active substances is attained after 2-8 hours.

The second phase of the main component concentration occurs within 30 hours after consumption means. Metabolites derived drug for 24 hours. Excretion occurs mainly along the bile - up to 70%. Other output together with the urine - up to 25%.

When applied to the skin surface agent concentration troxerutin in epidermal layers observed after 30 minutes. The drug penetrates the adipose tissue within 2-5 hours.

application

Dosage pharmaceutical remedies is calculated based on the severity and nature of the disease. Also takes into account the patient's age and individual characteristics of the organism.

For children up to 18 years

Means in both dosage forms is prohibited for use in children under 15 years.

formulation	Dosage	duration of therapy
capsules	3 times daily for 1 pc. Starting from the 2nd week, take 1 capsule 2 times a day.	not more than 1 month
Gel	3-4 times per day applied to the affected area.	no more than 10 days

The dosage can be adjusted depending on tolerability and severity of the disease. the therapeutic effects of the course may be extended if there is evidence and good tolerability of the drug.

adult

For pills. In the initial stages of the dosage is 1 tablet 3 times a day. Treatment is carried out over 2 weeks. Further treatment is carried out when assigning a similar or reduced dosage of 1 capsules per day 2 times. Duration of treatment - at least 1 month.

As a supportive treatment is assigned to 1 tablet 1 time a day. In the presence of diabetic retinopathy is assigned to 2 capsules 3 times a day. Duration of therapy in this case is not more than 1 month.

Gel. Applied from 3 to 4 times a day to the affected area. Rub with light massage movements. Permission is granted to use the tool under the bandages. Duration of treatment - no more than 1.5 weeks.

For pregnant

Troxerutin, according to the official statement, it is prohibited from taking in the 1st trimester. Next, decide on the possibility of using the drug made by a physician. The dosage form of the drug and established a specialist on the basis of pregnancy.

for elderly

The drug can be administered in old age only under medical indications. Data on the use of funds in this category of persons are missing or insufficient.

Contraindications

The medication has some limitations for use.

Contraindications:

• Children up to age 15 years;
• presence of hypersensitivity to the components;
• 1st trimester of pregnancy;
• during breast-feeding;
• the defeat of the duodenum and stomach ulcer;
• chronic form of gastritis.

A further limitation to the use of means (gel) is a violation of the integrity of skin. With high caution prescribed for chronic renal failure flow.

Overdose

When exceeding the prescribed dose specialist may arise negative reaction.

Systemic disorders:

• nausea;
• irritability;
• flushing of the skin;
• development of headaches.

With the development of drug poisoning symptoms should wash out the stomach and to use sorbents - smectite, activated charcoal. Cases of overdose gel were not registered.

Side effects

Troxerutin, instructions for use which indicates a possible development of adverse reactions at external use can lead to the formation of eczema, urticaria, dermatitis.

Side effects from the use of capsules:

1. Immune system: the development of hypersensitivity.
2. Central Nervous System: headache, migraine.
3. Cardiovascular system: flushing, a rush of blood.
4. Digestive organs, digestive tract: nausea, vomiting, pain in the epigastric region, bloating, flatulence, erosive ulcerous formations of structures in the stomach.
5. Skin and subcutaneous tissue disorders: pruritus, rash, erythema, urticaria.

With the development of adverse reactions is necessary to abandon the use of pharmaceutical remedies and refer to a specialist for advice.

drug interactions

When using both the drug and ascorbic acid is observed increased activity of the second substance. Thus, ascorbic acid has an inhibitory action on capillary permeability and vessel walls. Data on the interaction of a lack of gel formulation.

special instructions

When thrombotic lesions deep vein tromboflebicheskom syndrome does not prohibit concurrent use of agents possessing anti-inflammatory and antithrombotic effect.

In the treatment of edema due to the development of kidney disease, heart or liver, to apply the medicament in tablet form effectively. When using the self-medication should be strictly comply with the dosage and duration of treatment specified in the instructions for use.

If there is no therapeutic effect or feel unwell and severity of clinical need to stop taking the money and seek the advice of phlebologist.

The gel composition for external application must be applied only on healthy, undamaged skin.

This should avoid contact pharmaceutical remedies open wounds, lesions, mucous membranes and eyes.

Effective drugs is the simultaneous use of a gel base and ascorbic acid. Thus there is enhanced effect of ascorbic acid against respiratory infections, scarlet fever, and other allergic reactions.

If swallowed gel lacrimation observed development, nausea, vomiting, burning sensation in the mouth and profuse salivation. In such a case it is necessary to spend extra rinsing of the mouth and stomach. If necessary symptomatic treatment appointed

In the reaction of the gel and of the mucous membranes is the development of local reactions - pain, redness, burning, lacrimation. It is necessary to hold an emergency lavage with isotonic sodium chloride solution or purified water sodium. The procedure is performed to eliminate symptoms.

Venotonicheskoe agent does not adversely affect the ability to drive a motor vehicle or conduct work related to the increased concentration.

Conditions and terms

Store in a dark place is necessary at a temperature not exceeding 25 0C. Means must be protected from sunlight and away from children. Shelf life for capsules - 3 years from the date of manufacture for the gel - 2 years. Do not use after the expiration date printed on the package.

Conditions of supply of pharmacies troxerutin

Available without a prescription.

analogs

Troxerutin, instructions for use which indicates the intolerance of some components may be replaced by other drugs. The medicine has a number of substitutes for the active substance and pharmaceutical group. Appointed by such drugs with contraindications.

• Troksevazin. It is made in the form of a gel and pellets. The active substance is troxerutin. Medication indicated for the reduction of symptoms associated with the development of venous insufficiency, as well as mechanical damage, accompanied by edema and pain. Means is contraindicated in children under-age. Allowed to use during pregnancy, but only after consultation with your doctor. The dosage and duration of the course depends on the degree of damage. On average, the use of external funds should not exceed 10 days. Price - from 180 to 420 rubles. per pack.
• Troksevenol. The main active ingredient is troxerutin. It manufactures products in the form of gel base for outdoor use, as well as in the form of capsules. It belongs to a group angioprotectors contributing to the restoration of the microcirculation. Indicated for thrombophlebitis, venous insufficiency, bruises and sprains, accompanied by the development of edema. Also shows efficacy in the treatment of hemorrhoids and rheumatic soft tissue. The dosage is determined by the expert in view of the age and disease form. The cost of pharmaceutical remedies range from 165 to 225 rubles.
• Lioton. Made in gel form for topical use. The active substance - heparin. It is used for diseases of the superficial veins, varicose and trophic ulcers. It is also prescribed for injuries, bruises and sprains. It is contraindicated in the presence of open wound surface, accompanied by the release of exudate. Apply from 1 to 3 times a day. The duration of treatment is 10 days. Price - from 260 to 500 rubles.
• Flebopress. The main component of the medicament - troxerutin. It is produced as a gel for topical application. It belongs to a class angioprotectors and proofreaders microcirculation. Effective in an integrated approach with venous insufficiency, varicose veins, periflebit, as well as the formation of post-traumatic edema. Facilitates and eliminate symptoms with inflammation of hemorrhoids. Pharmaceutical remedies banned for use in children younger than 18 years, with chronic renal failure, as well as in the 1st trimester of pregnancy. Price - from 250 rubles.
• Fleboton. It is produced in the form of gel. It belongs to a class of bioflavonoids, angioprotectors. The active substance - troxerutin. The drug has kapillyarotoniziruyuschim and venotonic effects. Appointed in various pathological processes associated with the development of varicose veins. It can be used in children. Dosage is calculated taking into account the degree of disease severity. The duration of therapeutic effect is usually from 8 to 10 days. The cost of the drugstores of Moscow and the Moscow region - from 120 to 200 rubles.
• Venotol. Made in the form of a gel for the legs. The main active ingredient is trokseurtin. The tool is designed for the care of sick and tired legs, venous thrombophlebitis. It relieves inflammation, eliminates symptoms of swelling, restores microcirculation. Apply the gel to the affected area 2-3 times a day. Duration of exposure depends on the severity of the disease. It can be used during pregnancy and childhood, but before the application is recommended to consult a doctor. Cost - 65 rubles. per pack.

Medical patients is prohibited to pick their own analogues prescribing. Before using troxerutin or its analogues should consult with their physician or pharmacist and read the instructions for use.

Registration of the article: Mila Friedan

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