Rutin. That is, instructions, indications for use, which the body needs, in what foods contain. Preparations with vitamin P, as taking

Vitamins of group P (bioflavonoids) are essential elements for the health of human venous circulatory system. Currently, the most commonly used is the bioflavonoid rutin. Affordability and ease of routine instructions for use make it an indispensable source of vitamin P in medicine and cosmetology.

What is rutin and its role in the body

The peculiarity of vitamins P is that the body can not synthesize their own. They are found in foods of plant origin, or extracted from them for the production of medicines. The pure extract rutin (Rutoside) is obtained from the leaves of Ruta fragrant, buckwheat, green tea, dandelion and rosemary.

Rutin is important for the normal functioning of the human body:

• protect cell membranes from the adverse effects of free radicals;
• rejuvenates the body;
• strengthens innate immunity;
• strengthens the body's resistance to adverse external factors (climate, environmental, infectious);
• It stimulates the adrenal cortex;
• aligns hormones;
• It strengthens the vascular wall and protects them from sclerosis;
• normalizes blood and intraocular pressure;
• restores the metabolism;
• stabilizes the heart rate;
• It accelerates the healing of mucosal lesions in internal diseases;
• It is a method for the prevention of infectious diseases, varicose veins, scurvy;
• It smoothes the appearance of cellulite by improving lymph flow.

Daily rates for women, men, children

The daily requirement for routine healthy people is:

• for children up to 12 years - 20-25 mg;
• for teenagers - 25-40 mg;
• for adult women - 40-50 mg;
• for men - 50-75 mg;
• for people actively involved in sports or engaged in heavy physical or mental work - up to 100 mg, in a period of high stress and preparations for the competition - up to 120-130 mg.

Therapeutic routine norms vary widely from 100-150 mg per day for up to gipovitaminoze shock doses of 800-1000 mg in cases of acute venous insufficiency. The selection and dosage of the drug in each case determined by the physician.

Causes and symptoms of deficiency of vitamin E when needed supplementation routine

The main reasons are beriberi F:

• insufficient consumption of fresh plant foods, especially in autumn and winter;
• cardiovascular diseases;
• smoking;
• alcohol abuse;
• inflammation in the gastrointestinal tract (in this case, the vitamin E is not absorbed by the body, even if in sufficient quantity supplied with food);
• difficult working conditions: high temperature and chemical production;
• the uncontrolled use of antibiotics and aspirin.

Symptomatology of beriberi P in the body:

• impaired performance, drowsiness;
• pain in joints and muscles;
• weakened immunity;
• increased hair loss;
• acne rash on the face, back and chest;
• bleeding gums, periodontal disease;
• wanton appearance subcutaneous hemorrhage (petechiae) and bruises.

When these symptoms should consult a physician for the purpose of differentiation hypovitaminosis P of more serious disease and determination of treatment.

release Form

Release preparations containing rutin, for ingestion is carried out in 3 ways:

• Pills. Contents rutoside: 20, 50 and 500 mg. Packing: in packs of 30, 50, 100 and 250 pieces.
• Capsules. Rutoside Contents: 500 mg. Filling in jars of 120 pieces.
• Powders. Packing: plastic bags of 50, 100, 500 and 1000

For external topical application is available in the form of gels and ointments in tubes 40-50 g

Pharmacodynamics and Pharmacokinetics

It refers to a group of vitamins, with the following properties:

• angioprotective;
• antioxidant;
• decongestants;
• anti-inflammatory.

It reaches maximum concentration of 1-1.5 hours after oral administration and is stored in tissues and organs for 8-9 hours.

Cleavage at the vitamin active substances occurs as a result of alkaline reaction in the kidneys and intestine. practically not absorbed in the stomach. Excreted predominantly in the urine. The half-life is 10-25 hours.

pharmachologic effect

Mainly affects the venous vascular system of the body:

• strengthens the walls of blood vessels and capillaries;
• prevents vascular lesions of the retina;
• stabilizes blood pressure (by expanding the lumen of blood vessels);
• It thins the blood and prevents blood clots;
• It improves lymphatic flow in chronic venous insufficiency;
• corrects hypovitaminosis P;
• possess antiallergic properties;
• It improves the redox metabolism;
• It facilitates the introduction of the body of heavy metal ions.

Indications

Administration of drugs containing Rutoside appoint the following diseases:

• hypovitaminosis P;
• increased fragility vessels (bleeding from the nose and gums, the tendency to form internal hemorrhage and hematoma);
• violation of the venous outflow;
• hemorrhagic diathesis;
• varicose veins of the lower extremities;
• heart disease: endo- and myocarditis, coronary heart disease;
• heavy menstruation and dysfunctional uterine bleeding in women;
• hemorrhoids;
• lipodystrophy (cellulite);
• vascular thrombosis;
• diabetic retinopathy;
• Infectious diseases: scarlet fever, measles;
• radiation sickness;
• injury and frostbite of soft tissue.

Contraindications

Routines, instructions for use which informs about the absence of contraindications to the use, in addition to individual intolerance also recommended to receive 1 trimester of pregnancy, as the possible negative impact on the formation of fetus.

Side effects

Upon receiving the preparations containing Rutoside, the following side effects:

• headache
• heartburn;
• nausea;
• flatulence;
• diarrhea;
• sensation of heat in the face;
• skin reactions (using external means)

The occurrence of side effects associated, as a rule, in violation of the instructions for use of the drug.

Instructions for use

Rutin is a component of a number of drugs. Given their wide range and variety of release forms, instructions for use for each individual agent.

The daily dosage and duration of administration of the course determined by the physician depending on:

• disease for which treatment is assigned Rutoside;
• sex;
• age;
• weight of the patient;
• level of physical activity.

General rules for the use of drugs rutinsoderzhaschih:

• ingestion - during meals, washed down with water;
• externally - to the affected area, light rubbing motion until completely absorbed.

Overdose

Cases F hypervitaminosis extremely rare, but possible with uncontrolled reception rutinsoderzhaschih preparations. Manifested by nausea and dizziness. Since the substance is water soluble rutin, an overdose administered drinking liquids for rapid excretion of excess drug in the urine.

drug interactions

It proved higher efficiency routine interaction with other vitamins and active ingredients:

• Maximum efficiency is tandem with ascorbic acid (vitamin C) - in this combination improves the absorption of iron and penicillin preparations group; prevents reduction of hyaluronic acid in the body.
• Potentiates the effect of polyunsaturated fatty acids, selenium and zinc.
• When co-administered with anticoagulants accelerates the recovery of damaged capillaries.
• Improves the absorption of beta-carotene and succinic acid.

Negative reaction:

• Rutin reduces the efficiency of vitamin B1.
• Action weaken routine aspirin and oral contraceptives.

special instructions

In case of pregnancy with the use of drugs rutinsoderzhaschih their reception should be abolished.

Terms of sale and storage

Routines, instructions for use is determined by a physician, is available without prescription. Store any preparations should release form at room temperature, in a dry place, protected from light.

Shelf life rutinsoderzhaschih drugs - 2 years.

Preparations containing rutin: table names regimen

Name	The composition (active substance per 100 g)	The dosage regimen
Rutin (tablets, capsules, powder)	Rutoside 100% (in several embodiments, dosage)	Inside during meals with water in several stages. Maximum daily rate: Children under 12 years - 50 mg teenagers - 100 mg adults - 400 mg
Ascorutinum (tablets)	Rutoside + 50 mg Ascorbic acid 50 mg	Inside during meals with water, 1 tablet 2-3 times a day. admission course - 3-4 weeks.
Askorutin-D	Rutoside + 50 mg Ascorbic acid 50 mg. It does not contain in the composition aids sucrose and are allowed to receive patients with diabetes mellitus.	similarly askorutin
Rutaskorbin (tablets)	Rutoside + 50 mg Ascorbic acid 50 mg	similarly askorutin
Profilaktin C (Tablets)	Ascorbic acid 100 mg + 25 mg Rutoside	Inside during meals with water, dosage: children under 15 years - 1-3 tablets a day Adults - 2-5 tablets. admission rate - up to 30 days.
Troxerutin (capsules)	300 mg Troxerutin	Inside during meals with water, take 1 capsule 1-2 times a day. admission course - 2-4 weeks
Trokerutin (gel)	Troxerutin - 2 g	Topically to the affected area with light rubbing movements 2-3 times a day. The course of treatment -10-14 days.
Indorutin (gel)	Indomethacin + 30 mg Troxerutin 20 mg	Topically to the affected area with light rubbing movements 2-3 times a day. The course of treatment - 5-10 days.
Troxevasin (gel)	Troxerutin 20 mg	Topically on the affected area with light rubbing movements 2 times a day (morning and evening). The course of treatment - 7 days.

Price in drugstores of Moscow, St. Petersburg, regions

The cost of preparations containing rutin, fluctuates within certain limits, depending on the region of purchase.

The price range listed in the table below:

Name	Packaging	Moscow, rubles.	St. Petersburg, rub.	Regions rubles.
Ruthin	powder, 100 g of	300-350	300-350	250-275
Rutoside	50 capsules	700-800	700-800	750-850
askorutin	50 tablets	40-60	35-55	30-50
Askorutin-D	50 tablets	50-70	50-60	40-50
Rutaskorbin	50 tablets	40-60	35-55	30-50
With Profilaktin	30 tablets	30-40	25-35	25-35
troxerutin	30 capsules	350-400	350-400	200-300
Trokerutin (gel)	gel tube 40g	35-65	40-55	30-55
Indorutin (gel)	gel tube 45g	275	there is no data	there is no data
Troxevasin (gel)	gel tube 40g	200-350	250-350	150-250

List containing vitamin E products

Routines, instructions for use which is in the form of medicines may be obtained by a doctor, contained primarily in vegetable products.

Sources of flavonoids are stone fruits:

• plums;
• apples;
• apricots;
• cherry;
• grapes;
• nectarines;
• peaches;
• quince.

Citrus:

• lemons;
• grapefruit;
• oranges.

berries:

• Strawberry;
• chokeberry;
• raspberry;
• black and red currant;
• blackberry;
• sweet cherry;
• cranberries;
• gooseberry;
• strawberries;
• dog-rose fruit.

Green vegetables:

• sorrel;
• parsley;
• pepper;
• White cabbage;
• cauliflower;
• asparagus;
• spinach;
• garlic;
• green pea;
• zucchini zucchini;
• leaf salad.

As well as:

• tomatoes;
• olives;
• buckwheat;
• almond;
• green tea, Hibiscus;
• pollen.

It is important to know that vitamin E is easily destroyed by heat, but because of the above product should be consumed raw or subjected to gentle heat treatment.

Diet, balanced content of vitamin P

A diet rich in flavonoids not only saturates the body vitamin P, but also strengthens the immune system, has a powerful antioxidant effect, slows down aging.

Sample menu for the week, balanced content of vitamin E:

Breakfast	Dinner	Dinner
Day 1	Oatmeal with fresh berries or fruit. Sandwich with butter.	Fresh vegetables (cabbage, carrots, bell peppers) with vegetable oil. Boiled buckwheat. Meat dish.	Boiled egg. Rye bread with curd cheese, tomatoes and herbs.
day 2	Omelette with tomatoes and fresh herbs. Sandwich with cheese curd.	Salad of fresh vegetables (tomatoes, cucumbers, greens) with sour cream. Cauliflower baked with cheese.	Vegetables, grilled or vegetable stew (zucchini, pepper, tomato, carrot). Fish baked.
day 3	Bulgarian pepper. Buckwheat porridge with butter.	Appetizer of tomatoes, cheese with garlic and herbs. Green beans boiled. Poultry dish.	Cottage cheese casserole with raspberry and cherry.
day 4	Fruit salad (apple, banana, tangerine, apricot) with yogurt and muesli.	Egg salad and seasonal greenery (sorrel, chives, dill, parsley) with cream. Boiled potatoes. A fish dish.	Cream of pumpkin. Sandwich of wholemeal bread with salmon and cucumber.
day 5	Cottage cheese with fruits (pear, peach, nectarine). Bread with jam.	Salad with tomatoes, feta cheese and olives with olive oil. Fried eggplant.	Salad greens sheet with lemon juice and olive oil. Chicken breast.
day 6	Boiled egg. Sandwich with paste made of cottage cheese, chopped greens and walnuts.	Salad of radish and sour cream. Myasokapustnaya casserole.	Leaf lettuce with avocado and shrimp. Fish baked.
day 7	Rice porridge with fresh berries or fruit. Sandwich with butter.	Salad of pumpkin, apple and celery root. Stuffed zucchini.	Smoothies from sour milk and fresh berries and fruits. Low-fat cottage cheese with nuts.

To drink useful to use:

• green tea;
• broth hips;
• Herbal tea with leaves currants, cherries, mint;
• hibiscus tea;
• freshly squeezed juices from fruits and vegetables;
• natural berry fruit drinks (cranberry, lingonberry, seabuckthorn)

Prevention of vitamin E deficiency

In order to prevent hypovitaminosis P is necessary to use a sufficient amount of fresh plant foods. In the autumn and winter period can take courses dietary supplements containing vitamin P (e.g., pollen).

It is also important to abandon or minimize the consumption of alcoholic beverages and tobacco. Routines, instructions for use which is rather simple, is an excellent way to prevent beriberi R.

The consequences of vitamin E deficiency

Faced with hypovitaminosis, many people do not perceive it as a serious threat to health.

However, a lack of vitamin P in the body can lead to serious consequences:

• decrease in hemoglobin levels due to constant bleeding;
• tooth loss due to periodontitis gingival progression;
• increase the risk of internal bleeding (including microstroke);
• alopecia (hair loss);
• deterioration of the skin and hair;
• premature aging of the organism.

Therefore, when the first sign of a lack of vitamin E should see a doctor. It will help to correct diet, prescribe supplements containing rutin, and instruct on their use.

Author: hope Goss

Video of the routine, its beneficial properties and content in various products

The role of vitamin P:

How to identify a lack of vitamins in the body: