Chlamydial infection - vysokozaraznoe infectious disease, sexually transmitted, which leads to the development of inflammatory changes of the urogenital system, and has a significant impact on future fertility function.
The source of infection are those with asymptomatic or manifested chlamydia.
The mechanism of transmission - contact, ways of transmission - sexual and contact-household. It is also possible vertical infection of the fetus.
Manifestations of chlamydial infection
Symptoms in women:
- mucopurulent discharge from the vagina;
- pain in the lower abdomen;
- painful urination;
- intermenstrual bleeding, spotting after sex;
- pain during intercourse;
- infertility.
Symptoms of Chlamydia infection in men:
- mucous or mucopurulent discharge from the urethra;
- painful urination;
- pain in the lower abdomen with the spread of the perineum;
- erectile Dysfunction.
In addition, depending on the localization of the disease process in people of both sexes may experience isolation and discomfort in the rectal area, redness, tearing, pain in the joints.
Diagnostics
The following research methods used in the diagnosis of chlamydial infection:
- general analysis of blood and urine;
- dvuhstakannaya urine test (for women) and trehstakannaya urine test (for men);
- microscopic examination of the discharge from the urethra (men) or the urethra and vagina (in women);
- bacteriological examination of discharge from the urethra (men) or the urethra and vagina (in women);
- study scrapings from the urethra (men) or the urethra and vagina (in women) c polymerase chain reaction (PCR) method of direct immunofluorescence with monoclonal antibodies and plating on medium M'Coy ( "Gold Standard") for identifying chlamydia;
- study of immune status.
Treatment of chlamydial infection
Sexual partners are subject to inspection, and if necessary, treated. In the treatment of the infection should be advised to abstain from sexual intercourse without a condom to microbiologically proven cure.
By the choice of drugs used in Ugh, azithromycin and doxycycline are:
- 1.0 g of azithromycin inwardly once;
- doxycycline 200 mg once inside, followed by 100 mg 2 times a day for 7-10 days.
Azithromycin - broad-spectrum antibiotic from the group of azalides. It has been shown that acute administration of 1.0 g azithromycin not as effective as a 7-day course of doxycycline (200 mg / day). Side effects after the application of azithromycin occur no more than 10% of patients. In the treatment of complicated chlamydial infection according to the recommendations of the Ministry of Health of azithromycin administered in a course dose 3.0 g (1.0 1 g once a week).
In addition, the complex of therapeutic measures for chlamydia is recommended to include a low-energy laser therapy, prostate massage (Men) assignment immunomodulators, preparations improving microcirculation (pentoxifylline, escin, diosmin), antifungal agents (fluconazole, Nystatin).
As an alternative means for the treatment of Chlamydia infection used:
- inside clarithromycin 250 mg 2 times a day for 7-10 days;
- inside ofloxacin in 200 mg 2 times a day for 7-10 days;
- inside roxithromycin 150 mg 2 times a day for 7-10 days;
- spiramycin inwardly 3 MIU 3 times a day for 7-10 days;
- erythromycin inside of 500 mg 4 times a day for 7-10 days.
In the treatment of chlamydia, the following immunomodulating drugs:
- immunomaks 100-200 IU intramuscularly 1 time per day every other day, total 6 injections;
- imunofan intramuscularly or subcutaneously at 0.05 mg 1 time per day every other day, 10-15 injections;
- polioksidony intramuscularly or subcutaneously with 1 mg 6 times per day for 5 days, followed by 6 mg a day, total of 10 injection or rectum 1 suppository (6 mg), 1 time per day for 3 days, then 1 suppository every other day, 10 candles;
- TSikloferon intramuscularly 0.25-0.5 1 g once daily on the 1 st, 2, 4, 6, 8, 11, 14, 17, 20, 23, 26 and 29th day.
Criterion cure chlamydia - negative results of laboratory testing in the absence of clinical manifestations of disease.
This article is based on information of breast cancer - Independent publications practitioners