International Nonproprietary Name - Ketoprofen.
The preparation is available as a gel for rubbing into the affected area.1 g of the agent contains 25 mg of the active ingredient ketoprofen.
The preparation is available in the form of a gel of 30 g or 50 g in aluminum tubes.
Auxiliary components:
- ethanol;
- carbomer;
- lavender oil;
- diethanolamine;
- neroli oil;
- water;
- methyl parahydroxybenzoate.
The gel is clear, slightly cloudy or has a light yellowish tinge. It is classified as a non-steroidal anti-inflammatory drug for local use.
Article content
- Pharmacological action
- Pharmacokinetics of
- When is the application effective?
- The mechanism of action of
- The mechanism of action of
- The dosages and methods of application of the drug
- The cases of overdose
- Special instructions
- The opinion of medical practitioners
- The patients' reviews
- You need to know
- Pros and Cons of
- Buy and store
- Similar drugs
Pharmacological action
Has analgesic and anti-inflammatory effect. Reduces pain syndrome, eliminates swelling in the affected area, facilitates movement.
Pharmacokinetics of
When repeated external use of the agent( for example, 370 mg of gel) the concentration in the blood of the active substance is almost 100 times less than with a single internal intake of 150 mg of ketoprofen.
Ketoprofen is converted to acylglycuronide and is excreted from the body by the kidneys. The elimination half-life after the secondary rubbing is about 17 hours. Biological availability of the drug is small - about 5%.
When is the application effective?
Indications for use of Valusal are as follows:
- rheumatoid arthritis( chronic inflammation of the joints);
- spondylitis( inflammation of the spinal column);
- gout( retention of uric acid salts);
- inflammatory-degenerative lesions of the musculoskeletal system;
- back pain;
- neuralgia( peripheral nerve damage);
- myalgia( muscle pain);
- sports injuries( dislocations, sprains, ligament rupture, posttraumatic pains);
- combined treatment of inflammatory diseases of veins, lymph nodes.
Contraindications
The gel can not be used in conditions such as:
- , dandruff;
- eczematous skin lesions;
- open wounds;
- irritation;
- infected abrasions.
Mechanism of action
The mechanism of action is due to oppression of the activity of COX-1 and COX-2.
The pronounced analgesic effect of the gel is achieved through the suspension of the synthesis of prostaglandins and effects on neurotropic centers that promote the release of mediators of pain in the spinal cord.
Also, the drug fails anti-bradykinin action, blocks platelet aggregation, inhibits neutrophil activity in rheumatoid arthritis.
Dosages and methods of application of the preparation
The drug is applied externally, distributing on the affected surface with a uniform layer. The gel can be rubbed up to twice a day. The affected area can not be wound with a bandage.
Adolescents over 15 years of age can use the gel up to twice a day. The duration of treatment depends on the form of the disease and ranges from one to ten days.
Cases of overdose
With external use, the bioavailability of the drug is small, which is why the possibility of an overdose is unlikely.
Possible adverse reactions:
- dermatitis;
- eczema;
- hives.
In this case, the use of the drug is canceled, symptomatic and restorative treatment is performed.
Special instructions
VALUSAL gel is used for topical use. Avoid contact with eyes and mucous membranes. After use, wash thoroughly with hands.
The drug can increase the susceptibility to ultraviolet radiation( natural and artificial light), therefore it is recommended to avoid getting the damaged area of the body under direct sunlight during treatment, and also within two weeks after using the drug.
The tool does not affect the ability to drive and work with potentially dangerous devices. Cases of incompatibility of simultaneous intake of alcohol and the use of gel have not been identified.
Pregnant women, as well as planning a pregnancy, before using the drug should consult with a specialist. Application in the first and second trimester is permissible only if the intended benefit for a woman exceeds the possible damage to the fetus.
Breastfeeding should be discontinued at the time of use. Use of the drug before the age of 15 years is contraindicated.
No cases of drug interaction with other medications have been reported.
Opinion of practicing doctors
Comments of doctors who prescribe to their patients Valusal gel.
The preparation contains ketoprofen - a modern anti-inflammatory and analgesic substance. Due to its water-alcohol basis, the gel quickly penetrates into the epicenter of inflammation and the site of pain localization.
Thanks to this property, the gel acts quickly and efficiently. I want to note that none of my patients complained of side effects, unlike other similar drugs. The gel also contains essential oils, so the product can be used for massage. The agent can be used in physiotherapeutic procedures.
Sergey Leonidovich
Patient Reviews
This is what the patients say.
Valentina
Elizabeth
Nicholas
It is necessary to know
Tips for taking:
- should not be applied on irritated or damaged skin, otherwise irritations and rashes may appear;
- it is necessary to comply with the recommended dosage to avoid allergic reactions - it is better to first apply a little remedy to check how the body reacts to it;
- a good effect of the drug gives in combination with massage and rubbing.
Pros and Cons of
VALUSAL GEL is an affordable, effective analgesic and anti-inflammatory agent.
Helps with sprains, injuries, bruises, diseases of the musculoskeletal system and other disorders.
However, it should be used with caution in people with sensitive and dry skin, since ethanol in the composition can cause irritation and peeling.
Purchase and storage of
Available in tubes of 30g and 50g. The average price of Valusal gel in pharmacies is 200 rubles .
The drug should be stored in a dry place protected from the sun. The storage temperature is up to 25 degrees. Shelf life is two years. The product is dispensed in pharmacies without a prescription.
Similar tools
Analogues Gel valusa:
- Bystrumgel;
- Fastemel;
- Artrum gel;
- Ketonal gel.