Antimiller's hormone( AMG) is responsible for tissue growth and differentiation. In women, it is produced from birth by special cells of the ovaries. The production of AMH is continued until menopause. Antimulylerov a hormone, the rate at which women should be in certain limits, allows to define chances of natural conception in the concrete period of time.
Features of
The feature of AMG is that it is a local hormone, and its production is not controlled by the brain. Consequently, the amount of this substance in the blood entirely depends only on the functioning of the ovaries. Before the onset of puberty in girls, the level of this substance in the blood is not measured.
The amount of this substance is increasing during the pubertal period, and the maximum level is fixed in the blood of women aged 20-30 years. After 40 years, there is a constant decrease in the amount of this hormone, and it is not detected in the blood during the vaginal period or is less than 0.16 ng / ml. Since AMH is produced prepared for fertilization by eggs, any deviation from the normative indices indicates a violation of the reproductive function.
The level of this substance in women at different ages may differ. This is due to the fact that its production depends on a variety of external and internal factors. The norm of antimulylerovogo hormone in women in the reproductive period, according to a special table, is in the range of 2,2-6,8.
| Level AMG | Indicator( units change - ng / ml) |
| High | More than 6.8 |
| Normal | 4-6,8 |
| Normal low | 2,2-4 |
| Low | 0,3 -2,2 |
| Verylow | Less than 0.3 |
It is impossible to raise the level of this hormone by forced means, since it is produced by the eggs themselves. If the violation of their functions occurs from birth, antimulylerov hormone, the norm of which is very important for the possibility of conception, is produced in insufficient quantities. In this case, a woman faces infertility.
The production of AMG is not related to the amount of other hormones and does not affect the menstrual cycle. In addition, the production of this substance is not affected by nutrition, lifestyle and any other external factors. The age factor also plays no role, so very often women in 45 years are capable of conceiving a child. In the west, doctors recommend starting to control the level of this hormone in girls from 12 years of age. And if its indicator after reaching 14 years begins to fall, it is recommended to freeze eggs for future fertilization. It is also necessary to monitor this indicator after 35 years, in case the woman plans a pregnancy.
Conducting the
analysis Conditionally the analysis for the level of antimulylerovoy hormone can be considered a kind of marker of a woman's ability to conceive. Indications for it include the following pathologies:
- infertility,
- suspected premature puberty or delayed sexual development,
- unsuccessful attempted IVF fertilization,
- suspected polycystosis and ovarian tumor.
In addition to this analysis, the doctor can appoint, if necessary, the fact of the onset of early menopause against the background of malfunctions of the menstrual cycle. To conduct IVF, the determination of the amount of antimulylerovoy hormone is mandatory. This shows whether it is possible to conduct IVF and for what program. The blood for analysis is given in any specialized laboratory, and the results are given on hands for 2-3 days.
Before the test, you need to prepare correctly. The best time for giving blood is considered to be morning today. The fence of venous blood is carried out, as a rule, on the 3-5th day of the ovulatory cycle. Three days before the analysis, it is necessary to exclude physical overloads, and also to try to avoid stress and nervous overvoltage. Contraindications for this study are cold and infectious diseases, as well as poor health. On the day of the analysis, an hour before blood sampling is prohibited from smoking, eating and drinking.
Low level of
In most cases, a low level of antimueller hormone accentuates premenopausal changes that can occur in women after 40 years of age. During this period, the first malfunctions in the menstrual cycle also become noticeable. This analysis can predict the onset of menopause in about 4 years. This plays an important role in premature menopause up to 40 years, as it gives women a chance to have time to get pregnant. At a young age, the cause of the deviation from the norm in the direction of decline may be overweight or early puberty. Also, reducing the amount of hormones can overstrain the ovaries, which is often observed when taking hormonal drugs during chemotherapy.
Unfortunately, it is impossible to raise the level of anti-Muller hormone in the blood with any medication. Moreover, even if you do substitution therapy, you can hardly achieve real results that will make it possible to conceive naturally. But this applies to cases where AMG is initially produced in the woman's body incorrectly.
With regard to situations where the deviation from the norm is downward due to obesity or the early menopause, it is first of all necessary to eliminate the initial causes that lead to a failure in the production of the hormone by the oocytes. To delay the menopause, modern methods of hormone replacement therapy are often used, but you can get rid of excess weight with the help of a nutritionist. Very rarely, the reduction of antimulylerovoy hormone associated with stress, so after the normalization of the life situation and proper rest the amount of the substance will go back to normal.
If, against a background of a low level of AMH, a diagnosis of infertility is being made, one should not think about how to increase the amount of this substance in the blood, including folk methods, but about how to stimulate the ovaries to produce healthy eggs. Today traditional medicine offers quite effective methods for solving this issue. If it is impossible to provide pregnancy naturally, you need to consider alternative options for the birth of a child: IVF, the use of donor eggs or surrogate motherhood.
Increase in AMG level
A significant increase in the level of AMG indicates the presence of serious pathological changes in the female body. It can be:
- polycystic ovary,
- granulomatous neoplasm in the ovaries,
- no ovulation,
- delay in sexual development.
It should be known that harmful habits, for example, alcohol abuse and smoking, can lead to an increase in anti-Muller hormone. Also, the increase in the amount of this hormone in the blood is observed against a background of stressful situations or the presence of serious chronic diseases.
If the excess of the norm of this substance is detected, the doctor necessarily prescribes additional studies, and then prescribes treatment aimed at normalizing the amount of hormones. As a rule, the prognosis is always positive if the woman complies with all the medical recommendations and prescriptions.
The most frequent pathology, in which the level of antimulylerovoy hormone is increased, is polycystic ovary. In this case, treatment involves a review of diet and exercise. Special therapeutic measures are also being taken to normalize metabolism, especially carbohydrate metabolism. If the level of hormones remains elevated and the desired pregnancy does not occur, surgical methods of treatment can be applied.
In any case, if the analysis showed a deviation from the normal value of AMG, one should not be upset. It is necessary urgently to address to the qualified experts: to the endocrinologist and reproductologist. After completing additional surveys, they will find a solution to the problem, and the woman will be able to give birth to the child.
