Assays for acne are needed for the treatment of chronic skin diseases. Open or closed comedones appear on the face in the form of nodes, papules.
How hormones affect acne development
Acne on the face occur in young people under 18 years of age, but sometimes remain with a person to a great age. Dihydrotestosterone (DHT), facilitates the formation of acne on his face. The tendency to acne adjusted α-melanocyte stimulating hormone, insulin, corticotropin.
The pathogenesis of acne is associated with androgens, estrogens, progesterone, adrenocorticotropic factor (AKGG), glucocorticoids, growth hormone.
Analyzes on hormones in acne need to take patients with exacerbations short, and people-tolerant standard therapy. Research on hormones is recommended to take in case of acne late (after 30 years).
An increased amount of androgens (hyperandrogenism) in women leads to acne. Hormones need to be checked regularly, ie. A. Comedones in the form of nodules, cysts indicate a large amount of androgen in the body.
Preparation for analysis
Depending on the patient's symptoms the doctor prescribes pass tests:
- the presence of thyroid-stimulating hormone and adrenocorticotropic;
- thyroxine;
- cortisol;
- total testosterone;
- hydroxyprogesterone;
- Anti-Müllerian hormone;
- estradiol.
For the treatment of acne pass tests for pituitary prolactin. The patient was conducting research on FSH and LH hormones.
Analyzes must pass after special training.
On the initial data are influenced by such factors as:
- exercise stress;
- emotional stress.
To face was clean, with no trace of acne, you need to limit the use of drugs.
Pass tests, observing the following rules:
- They come to the lab to 8 o'clock in the morning.
- Before the procedure should not drink alcohol, it is necessary to eat moderately, to eliminate physical stress, no access to the sauna, solarium, avoid stressful situations, people need to rest for 10-15 minutes.
- During the week prior to the procedure is necessary to refuse treatment with medicines and hormones.
- Should stop smoking for 3 hours prior to the date of analysis.
What analyzes to hand with acne
Many patients are interested in what analyzes to hand with pimples on his face.
The survey includes: the study of the skin in the presence of the pathogen and parasite tests on hormones. Must pass with pimples on his face blood biochemistry, undergo ultrasound and X-ray.
When acne in women prescribed tests for hormones. Androgens during sexual activity leads to the appearance of acne. Analysis confirmed in many cases hormonal changes in the body.
In some cases, it is advisable to carry out a study on the sensitivity to AB.
Research is required if the woman appeared acne for the first time after 30 years. Some patients having clinical symptoms of hyperandrogenism, t. To. They increase the activity of male hormones. Irregular monthly cycle and the appearance of the black pigmentation of the skin, as well as obesity require mandatory checks.
steroid hormones
Tested for Glucocorticoids (steroids) is necessary for acne, t. K. Treatment with drugs of great benefit. They are used only on prescription for the treatment of acne. Excessive use gives rise to problems.
It is necessary to conduct a survey for the presence and amount of such glucocorticoid:
- hydrocortisone;
- cortisone acetate;
- prednisolone;
- methylprednisolone;
- dexamethasone.
Steroid hormones are applied to the face only if the bacterial and fungal microflora is normal. Analyzes with acne prescribed when necessary to eliminate the inflammation on the face for a few days.
Apply an ointment containing a steroid hormone, within a week.
Effectively it operates with the composition 0.1% triamcinolone for 7 days.
If the patient ignores the advice of doctors, are shown side effects of corticosteroids:
- metabolic disorders;
- osteoporosis;
- mental illness;
- Pathology of the adrenal glands;
- infection;
- immunosuppression;
- cataract;
- myopathy;
- diarrhea;
- stomach ulcer.
If the acne badly inflamed, steroids are used. Inside the inflammatory focus administered Triamcinolone acetonide that is diluted with 0.9% sodium chloride at a dose of 2.5-5 mg / ml. Steroids are used for the treatment of secondary inflammatory processes after application Isotretinoin. Sometimes it takes large doses of systemic steroids, led away for a minor period of time.
levels of testosterone
Acne is an inflammatory process of the hair follicles. Analysis for testosterone the doctor prescribes in case of severe disease. Testosterone is produced in the male body. At high concentrations of the hormone arises increased activity glands on the face. Hyperandrogenism appears as a result of malfunction of the pituitary gland, the ovaries, the hypothalamus, adrenal glands.
Man with excess hormone complains about the greasy hair and hair loss, prostate gland adenoma, emotional imbalance.
Normal component hormone - 5,5-42pg / ml.
Changing the amount of biologically active substance leads to hypertension, ischemic heart disease, cancer. The analysis is from 800 to 1200 rubles.
estradiol
Estrogen is a female hormone is produced in the ovaries. It affects the formation of collagen, the water balance, the sebaceous glands. If hormones fails, there inflammatory skin formation, wrinkles, decreasing the protective properties of the epidermal layer.
Blood tests for estradiol is necessary to establish the amount of hormones in the blood of men and women. It affects the work of skin glands. The analysis is a simple procedure, not hazardous to health. To carry out the research necessary not to take food and water for several hours before the procedure.
cortisol
Needed in a stressful situation. It distributes glucose, supplying it to the brain. Cortisol increases the amount of sugar in the blood, increases the level of insulin. Hormone in the blood serum, found in large quantities, is a sign of adrenal disease.
For the treatment of acne are conducting research AKTT stimulation or dexamethasone suppression. If you use the form ovarian androgens, indicators remain normal, and if the disease adrenal their quantity fall after ACTH stimulation as a result of the sample with Dexamethasone.
Results and Treatment
Acne can be eliminated using hormonal treatments. They are prescribed to patients with hyperandrogenism, and in severe cases, when the patient is often exacerbated acne.
Apply the following drugs:
- AR blockers;
- oral contraceptives;
- steroids;
- inhibitors of 5-alpha-reductase.
Spironolactone belongs to AR blockers. The preparation possesses antiandrogenic and antialdosterone effect. It reduces the production of testosterone by affecting enzymes. The dose for the treatment of acne is 50-200 mg 1 time per day after meals. The drug is not very effective.
Flutamide is used to treat acne, prostate cancer, baldness. The physician sets a dose of 62.5 to 500 mg / d.
Side effects of the drug manifested by pain in the chest, stomach disorders, decreased libido. In some cases, it develops hepatitis during which depends on the dose of the drug and the patient's age.
