Determination of Rhesus (Rh) of the fetus by the mother's blood is important as it will show that the course of pregnancy and the possible risks to the fetus. In case of a mismatch of this parameter in the future of the child and parent reaction may occur rejection by the mother's body, which will cause miscarriage or fading pregnancy.
why define
Rhesus-conflict threatens development and childbearing, with a particularly sharp negative signs manifest themselves in cases where the mother has a negative Rh factor, and the child - positive. In 80% of cases without receiving means, suppressing the immune system of pregnancy is interrupted naturally. The remaining 20% is the situation when the child is born with abnormalities, are often incompatible with the further activity.
Assay for determination of fetal rhesus factor is basic, so it is administered immediately after the clinical setting women account.
How is the study
According to modern methods of analysis of fetal Rh-factor is produced by non-invasively at 12 weeks of gestation. The study is based on PCR - polymerase chain reaction that allows you to draw conclusions about the parameters of interest to the fetus by taking biological material from the mother's body. As a last favor venous blood containing the DNA of the child particles, which in no way harm the pregnancy.
This embodiment allows the study to determine fetal rhesus blood group and probable, and to identify the effectiveness destination immunoglobulin response in the absence of production of antibodies designed to destroy the foreign object body.
Results are available in 3-5 days after the delivery of the material, and, based on the doctor makes a further prediction.
In rare cases, no drugs are not appointed and control is carried out only by means of ultrasound.
Rhesus conflict
Status of Rhesus factor determined by the presence of the protein covering the surface of the erythrocyte. His absence means Rh negative and vice versa. The incompatibility of these parameters results in the development hemolytic disease of the fetusRelated to transport baby red blood cells in the mother's blood through the placenta. This causes the formation of antibodies by the immune system that contribute to the disintegration of fetal erythrocytes, it entering the bloodstream, ie. K. A foreign object is determined embryo.
Diagnosis of the child shall be made by ultrasound. External symptoms of deviation is as follows:
- fluid accumulation in the soft tissues of the fetus and, as a result, is visible on the ultrasound edema;
- To change the default posture of the embryo.
Due to the swelling of the abdomen of the fetus feet are out to the sides, and the umbilical cord thickness slightly higher than normal, which is why there is also a slight change of position. Upon detection of such symptoms should undergo an analysis to determine the child's Rh factor.
If immunological incompatibility is confirmed, the pregnant woman should undergo periodic examinations throughout the term.
To reduce the possibility of patient complications administered intravenous immunoglobulin to eliminate antibodies provoking hemolytic disease of the fetus.
This deviation occurs only in the case where the maternal blood is Rh-positive, ie. K. A negative value conflict situations can not arise. However, if the parents have different Rh factors, the woman should be screened for 12 weeks of pregnancy to avoid the likelihood of disease.
Furthermore, it is assumed that the first conception antibody provoking hemolytic disease without produced, so the problems with child-bearing should not occur, but each subsequent pregnancy risk will increase.
