Ulcerative diseases of the gastrointestinal tract are quite common among other pathologies of the digestive system. Not a small role in the treatment of this problem is played antisecretory drugs. The pharmaceutical industry provides a wide range, due to factors such as price, efficiency, contraindications, brand popularity. The answer to the question, it is better to ranitidine or omeprazole in full can give only a doctor examining the totality of the patient and his disease data.
Selection of the optimal drug
Despite the fact that ranitidine and omeprazole belong to the same group of drugs, the differences between them still significant. To understand the difference between ranitidine from omeprazole need to consider their properties separately.
ranitidine
The principle of action of the drug based on the blocking of histamine receptors located in the gastrointestinal mucosa. This reduces the formation of hydrochloric acid. Ranitidine taken the course. Together with the admission means of enveloping the drug less effective.
Ranitidine is shown in the following cases:
- Peptic ulcer or gastric erosions and duodenal ulcers;
- Prevention of disease is acute;
- Gastritis, accompanied by high acidity;
- Heartburn;
- Reflux esophagitis;
- Gastric surgery.
Among the shortcomings should be noted addictive to the drugRequiring constant increase in dosage. increases sharply after stopping Ranitidin of gastric juice. Side effects include the possibility of allergic reactions, as well as increased production of gas and soft stools.
omeprazole
It adjusts the proton pump, which is responsible for regulating the production of gastric juice. It has the prolongation effect by reducing the activity of enzymes and peptides.
Use of the drug is recommended for:
- Stomach ulcer;
- In the treatment of Helicobacter pylori;
- Reflux esophagitis;
- gastrinoma;
- Formation of openings in the esophagus (hernia);
- Preparation for the surgery and the period after it;
Contraindications are similar with ranitidine.
Differences between omeprazole and ranitidine
Despite the similarity of the action difference between ranitidine and omeprazole is still there:
- Mechanism of action. Both drugs are antisecretory agents affecting the secretion of hydrochloric acid in the stomach. But if Ranitidine simply blocking its formation, omeprazole is able to neutralize the already formed acid, which is more efficient effect on the healing of gastric mucosal injury and significantly accelerates recovery;
- Product form. Omeprazole is produced in powder form for the preparation of injections, as well as in the form of enteric capsules and tablets. In Ranitidine exists only in tablet form;
- The allowable age of the patient. Omeprazole is allowed to take 5 years, while Ranitidine is allowed only from 12 years old;
- To ranitidine occurs addictive, omeprazole does not have this drawback. However, cases in which the patient does not respond to omeprazole were recorded. In cases where treatment is recommended to administer ranitidine;
- It was found that the effectiveness of antisecretory omeprazole is 2-10 times higher than the effect of Ranitidine.
Compatibility Omeprazole and Ranitidine alcohol
It should be noted poor compatibility drugs with alcohol. At the time of admission, doctors recommend to refrain from taking strong drinks.
conclusion
Of the known analogs of omeprazole is also possible to allocate Omez and famotidine.
It should also be remembered that as drugs of similar action taken together with Ranitidine Omeprazole inappropriate. Despite the fact that most experts agree that the PPI group drugs are more advanced and effective than H2 blockers, assign exclusively medicament must physician based on examination of the patient, the severity of the disease and its individual features.
sources:
Vidal: https://www.vidal.ru/drugs/omeprazol__3120
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 83097c54-4fcd-4122-b96d-1b90b38d8823 & t =
Found a bug? Select it and press Ctrl + Enter
