Medical classification of antibiotics based on their chemical structure, mechanism of action, activity, and danger to the body. The article is devoted to the question of which group of antibiotics include Augmentin - a popular tool for the treatment of pneumonia and other infectious diseases of the respiratory system.
Modern classification of antibiotics
Antibiotics - drugs that suppress the growth, development, reproduction of pathogenic micro-organisms.
The most important classification of medicines data - origin:
- natural.
- semisynthetic.
- synthetic (natural analogues).
Next equally important - Classification of the chemical structure:
- beta-lactams;
- macrolides;
- tetracyclines;
- aminoglycosides;
- chloramphenicol;
- fluoroquinolones.
Antibacterial agents are different mechanisms of action:
- stop protein synthesis by microbial agents, the effect on ribosomes function;
- violation formation of nucleic acids;
- suppression of cell wall;
- Stop synthesis of various structural components, purine and pyrimidine bases;
- disruption of the respiratory chain.
Many antibiotics have toxic effects:
- Aminoglycosides, gentamicin toxic to the middle ear and kidney, with incorrect and uncontrolled use causes serious side effects;
- Vancomycin is also dangerous to the organ of hearing;
- Tetracyclines are contraindicated in pregnancy because they have a pronounced teratogenic. In men, long-term use violates the sexual function, up to infertility;
- Penicillins low toxicity, but are not recommended for use in people with allergies.
Which group of antibiotics include Augmentin origin
Augmentin - combined formulation in tablets and solution. It includes a semi-synthetic antibiotic amoxicillin and clavulanic acid required for effective treatment of diseases caused by resistant strains of microorganisms. Semisynthetic origin means that obtained by culturing fungi activity products are modified in the laboratory. Semisynthetic antibiotics have fewer side effects, have the highest activity.
Chemical structure Augmentin
Group Augmentin antibiotic related to penicillin. The main drawback of the beta-lactam drugs - are ineffective against microorganisms that produce beta-lactamase. Augmentin contains clavulanic acid, that solves this problem and inhibits the action of enzymes, a microbe.
Which group is the Augmentin mechanism of action and spectrum of activity
Augmentin relates to a group of antibiotics with a broad spectrum of activity. The drug acts on Gram-positive and -negative bacteria, bacilli, Streptococcus, Staphylococcus, Clostridium, peptostreptokokki, Haemophilus, Leptospira, Borrelia, Klebsiella, Salmonella and producing beta-lactamase bacteria.
The main mechanism of action of Augmentin connected with the violation cell wall formation of the elements. As a result, cells lose their ability to growth, development, reproduction, eventually dies.
Augmentin toxicity
Augmentin belonging to the group of penicillins causes low toxicity of the drug. Augmentin under constant supervision of a doctor can be used even during pregnancy and for the treatment of the child. The most serious drawback of the group of penicillins - allergic danger high. Of all antibiotics anaphylactic shock in susceptible individuals often cause it penicillins.
conclusion
The antibiotics include penicillin group Augmentin, Amoxicillin, Bitsillin, Ampicillin and other medicines. Augmentin - semisynthetic agent of low toxicity and effective against a broad spectrum of microorganisms. All these properties are in more or less common to all antibiotics penicillin.
sources:
Vidal: https://www.vidal.ru/drugs/augmentin__96
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 181e9388-c7af-4899-a60b-cbf46ad9e251 & t =
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