HCG for 4 weeks' gestation: the norm, what should be the level of

Plasma concentrations of hCG at 4 weeks of gestation vary from 7,100 to 27,000 mIU / mL. Abnormalities in the fourth week do not necessarily indicate a pathological process development. Concerns should cause reduction of hCG, which indicates the loss of or delay in fetal development.

How to determine the level of

Gonadotropin determined using a biochemical analysis of urine and venous blood. For rapid detection of pregnancy, there are rapid tests. After contact with their urine HCG reacts with a chemical reagent which is impregnated paper. As a result, close to the control band appears even 1 line. The accuracy of the study is more than 95%.

Hormones in the blood flows more quickly and in greater numbers than in the urine. Therefore it is necessary to pass the laboratory analysis, if necessary, confirm the conception in the early stages. The study reveals the existence of an embryo at 1-2 weeks after fertilization.

Most often, the early survey administered to women during IVF, to assess the state of podsazhennogo embryo to confirm or deny its implantation in the lining of the uterus. Also tests help to identify the pathological process in the reproductive organs, intrauterine fetal abnormalities.

To confirm pregnancy treated in the laboratory at a delay of menstruation for 7-8 days or after 3-4 weeks from the last menstrual period.

To eliminate the risk of false results, conducted 2 analysis at intervals of 3-4 days.

If the follow-up study shows the value of hCG greater than the first rate by 1.5-2 times, confirmed conception. In the normal course of embryonic development gonadotropin will increase twice every 24-48 hours.

For laboratory examination is necessary to prepare:

• 6 hours is forbidden to use the food and any drinks;
• be receiving 0.5 liters of water without gas;
• 2 hours do not smoke;
• can not drink alcohol for 2 days;
• 2 days to cancel any possible drugs that can affect the rate of HCG for 3-4 weeks of fetal development, the work of the endocrine glands or the rheological properties of blood.

Donating blood is necessary in the morning in a calm state. Stress and emotional upheaval may distort the results.

What should be the indicator of normal

What should be the concentration of the hormone in the four weeks of pregnancy depends on the state of health. Analyzes allow time to identify fetal abnormalities in the fetus and start drug therapy to reduce the risk of complications.

HCG at 4 weeks of gestation is from 7,100 to 27,000 mIU / mL. The average value is considered to 11,000 mIU / mL. If conception does not occur, hormone component is less than 5.6 mU / ml.

If a woman is pregnant, there is a constant growth rates of hCG. To date at 10-14 weeks gonadotropin level should reach a maximum value - 128,000 IU / ml. To a 6-9 month pregnancy rate of 3000-78000 hCG mIU / ml.

The causes of variances

If the index of gonadotropin in urine or blood deviates from the upper or lower limit of normal, more than 20%, there is a risk of sexual or endocrine disease. Reappointed specimen collection. When not observed gonadotropin rise in serum hCG levels or decreased, at week 4 may develop:

• ectopic implantation of the ovum;
• fetal death;
• fetal growth retardation;
• fetal implant inherent IVF;
• placental insufficiency;
• spontaneous abortion.

For statement of the diagnosis the patient is sent for an ultrasound. If ectopic embryo attachment there is a slight decrease in hCG, therefore, to determine the precise location of the ovum only helps ultrasound. When fetal death gonadotropin levels about a week can remain stable and then decline sharply. In parallel, there is a thickening of the endometrium. Miscarriage occurs.

An abnormally high rate of gonadotropin at 4 weeks of gestation is often indicative of the simultaneous development of 2 to 4 embryos. Multiple pregnancy results from the separation of the eggs into several equal parts. Danger to the life of the mother and children in this case. You should not worry if the high content of hCG suggests expressed toxicosis.

A slight deviation from the norm may indicate preeclampsia, gestational diabetes. In other cases, the excess hCG says:

• molar pregnancy, adenoma chorions;
• anencephaly;
• incorrect use of hormonal medications;
• the risk of Down's syndrome in the unborn child;
• hydrocephalus.

At 4 weeks of gestation may develop chromosomal mutations, fetal anomalies during the laying of the vital organs and systems of the fetus. In the event of assigned medication hormones. The embryo is too small to detect any minor problems in its development, so screening is carried out from 11th to 14th week of pregnancy. Ultrasound is conducted for a period of 2.5 months.