Timolol gel for hemangioma. Reviews, instructions for use

Timolol - ophthalmic gel, which can be used not only for eye diseases, but also for the purpose of getting rid of small hemangiomas in children of preschool, primary school age. The drug has specific properties and, with atypical use, allows to eliminate the neoplasm without surgery.

Release form

The drug is produced in the form of an ophthalmic gel and drops for topical use. For the purpose of treating hemangiomas, it is usually the gel that is used, since it is slowly distributed in the tissues, providing a therapeutic effect.

The gel is transparent, has no color and no pronounced specific aroma. It can be packaged in small plastic containers of 10-15 ml, as well as disposable tubes of 1 ml. A description is attached to the medicine in any container, which indicates all the nuances of use, possible contraindications for therapy.

Vials of 10-15 ml are placed in cardboard boxes. Miniature containers of 1 ml can be placed in a separate polyethylene bag or cardboard box.

Chemical composition

Timolol is a hemangioma gel containing the substance timolol maleate. Due to it, the main therapeutic effect is realized.

The composition of the product contains auxiliary ingredients:

• Purified water.
• Hydrochloric acid.
• Sodium hydroxide.

Additional substances have no medicinal properties. The concentration of the active ingredient is 0.1%, but different pharmaceutical companies may produce the drug with different concentration of the ingredient. I also meet a remedy with a dose of 0.5% of the main substance.

Pharmacological properties

The drug belongs to the group of beta-blockers, has pronounced antianginal, antiarrhythmic and hypotensive properties. But such properties are provided only when the medication is used in an oral dosage form.

External use of beta-blockers is justified in the case of hemangiomas in patients of primary school and preschool age. The drug stops the progression of a benign neoplasm.

The action of the drug applies only to the affected area. The medication prevents the development of complications at the site of application if the child has concomitant symptoms.

Pharmacodynamics and pharmacokinetics

Hemangioma is a benign vascular neoplasm that most often appears on the skin of the body or scalp of children. Usually, the focus appears before the age of 1 year, after which it gradually increases or disappears.

Medicines from the group of beta-blockers, when applied topically, stimulate the resorption of the neoplasm. Upon penetration into the structure of the tumor, its development stops. Additionally, there is a gradual decrease in the size of the neoplasm and a decrease in the risk of degeneration of benign cells into atypical cells.

When used locally, the absorption of the components of the composition into the blood occurs in a minimal amount. The spread of the substance throughout the body is rapid. The blood dose increases with prolonged use and extensive lesions.

The processing of the ingredient when it enters the systemic circulation is carried out in the patient's liver. The evacuation of the decay products of the active substance occurs with the help of the kidneys. In the presence of skin lesions in the area of ​​neoplasm, more intensive absorption of the ingredients of the composition into the blood is possible.

Disorders of the urinary organs slow down the process of removing the ingredients from the body.

Indications for use

Timolol is usually used to relieve symptoms of pathologies of the cardiovascular system of varying severity, as well as eye diseases. But the ophthalmic gel can be used to get rid of hemangiomas in children of different ages.

Sometimes the drug is prescribed for adults, if the specialist considers it appropriate, and other methods cannot be used for various reasons. Experts pay attention that the use of the gel in a specific way is necessary in the case of intensive growth of a small neoplasm in children.

Contraindications

The drug for external use is considered relatively safe, but it is not always allowed to use it for the treatment of children and adults.

Experts consider the following conditions to be the main contraindications:

• Intolerance to the components of the composition and a tendency to such reactions in history. Often, the patient learns about intolerance after the start of use, therefore it is better to first test for sensitivity to the components of the composition.
• The presence of purulent foci in the area of ​​the neoplasm. The use of the drug can provoke an aggravation of symptoms.
• Extensive lesion area. With a minimum and medium size of the tumor, the medicine helps to get rid of the problem. But large neoplasms require other treatments.
• Chronic heart failure, accompanied by a decrease in blood pressure. Children usually do not have these disorders, but adults should not be prescribed topically when diagnosed.
• Cardiogenic shock.
• Damage to the skin in the area of ​​the intended application of the gel. After restoring the integrity of the skin, the use of the drug is allowed according to indications.
• Obstructive pathology of the lungs and bronchi. Despite the minimal systemic absorption, the drug in this case can provoke negative reactions, aggravating the course of the pathological condition.
• Atrioventricular block of a neglected form.

Relative contraindications for treatment include the progression of a dermatological disease. For example, in acute psoriasis, dermatitis, or eczema, the medication can irritate the lesions. Atopic dermatitis often worries children in the first year of life, in this case, treatment is carried out with extreme caution.

If the child suffers from thyroid pathologies or diabetes mellitus, the doctor decides on the appointment of the drug after a preliminary examination.

At what age can a drug for hemangioma be used?

Timolol is a gel for hemangioma, which is allowed to be used for patients older than 1 month, if necessary. Therapy for newborns is carried out in exceptional cases, if the intended benefit is greater than the possible harm. Treatment is supervised by a specialist.

Instructions for use, dosage

The medicine when diagnosing hemangioma is used only externally according to a scheme defined by a specialist. The standard method involves applying a minimal amount of gel only to the affected area.

Experts recommend performing the manipulation step by step:

1. Wash hands thoroughly.
2. The area to be treated must also be dry and clean. You should not apply the medicine if there is contamination on the tumor; it is better to pre-carry out hygienic procedures.
3. The gel is applied directly to the neoplasm in a minimal amount, trying to exclude the likelihood of large quantities of it getting on healthy tissues. If the drug does get on the skin around the tumor, it must be carefully removed with a napkin.
4. The procedures are carried out 2 times a day at approximately equal intervals. The duration of treatment in each case may differ depending on the size of the neoplasm and the tissue response to the drug. On average, the duration of the course is 2-4 weeks.

During the period of application, it is necessary to monitor the condition of the tissues in the area of ​​the neoplasm. Any negative symptoms should be a reason for immediate medical attention. When applying the gel, it is important to prevent the tip of the bottle from contacting the tissue. This can lead to the entry of microbes into the gel and their multiplication, which will reduce the effectiveness of the drug.

Side effects

Timolol is a gel for hemangioma, which can provoke negative reactions, despite minimal absorption into the systemic circulation. In this case, complications can affect not only the area of ​​application, but also the work of internal organs.

Damage area	Most common complications
Nervous system	Complications with prolonged use can affect the functioning of the nervous system. A child or adult patient may be irritable, troubled by insomnia, attention disorder, and memory impairment. Performance and physical activity are significantly reduced. Negative reactions are associated with the intake of a larger amount of the substance into the body than when using the gel in short courses.
Respiratory system	A patient's history of pathologies of the respiratory system increases the likelihood of complications from this system. Some people report shortness of breath, difficulty breathing, and a cough that gets worse with exercise. After refusal to use, the symptoms usually disappear on their own, but the use of medications may be required to eliminate the manifestations.
Digestive system	Digestive disorders with long-term treatment are not so common, but such complications can occur in older children and adults with diseases of the digestive system in anamnesis. Some people report nausea and pain in the stomach, upset stools, thirst, and indigestion.
Leather	Allergy to the drug is manifested even in patients who do not have a tendency to such reactions. The condition is accompanied by the appearance of a rash on different parts of the body, itching and burning, peeling of the skin. When scratching the affected areas, the outer layer of the skin is damaged, which worsens the condition and increases the likelihood of infection.

Adverse reactions are considered a reason to discontinue therapy and visit a doctor. In children, they usually disappear without special treatment, but adults often require medication.

Overdose

External use in most cases does not lead to the development of an overdose, even with a long course and application in large quantities. Despite this, doctors cannot rule out the likelihood of such reactions in individual patients.

In case of an overdose, the aggravation of negative reactions, as well as the general condition, is possible. An acute course of an allergic reaction is usually observed with the addition of complications from the mucous membranes.

There is swelling of the mucous membranes of the eyes, mouth and nasal passages. In this case, patients may be disturbed by allergic rhinitis and conjunctivitis. Puffiness is accompanied by severe itching and redness. As the symptomatology progresses, lacrimation joins, a large amount of viscous mucus is released from the nasal passages.

One of the most dangerous manifestations of an overdose is Quincke's edema, in which suffocation may develop against the background of edema of the mucous membranes of the throat. If such reactions occur, you must immediately stop using the medication and visit a doctor. Treatment in this case is carried out in a hospital under the supervision of a doctor.

special instructions

Timolol is a gel for hemangioma, which can only be used as directed by a doctor and in the presence of certain indications. It is forbidden to use the medicine at home on your own. It is especially important to observe this rule in the case when a hemangioma appears on the body of a preschool child.

Before starting treatment, it is recommended to test for sensitivity to the components in the gel. To do this, apply a small amount of the product to the clean and dry skin of the inner side of the forearm and leave it for a day. The doctor evaluates the reaction of the skin every 24 hours. If redness, swelling and rash appear in the area of ​​application, do not use the product. The absence of reactions confirms the possibility of using the gel for therapeutic purposes.

After 2 weeks of treatment, the specialist evaluates the result of the therapy. It may be necessary to prescribe other means, but more often the treatment is prolonged if the desired effect is not achieved.

Drug interactions

The drug is not prescribed concurrently with drugs that are also intended for external use. The drug does not affect the action of systemic medicines, therefore it is allowed to simultaneously use the funds if necessary.

Only in some cases do experts insist on a separate use of drugs. It is forbidden to apply funds externally without a doctor's prescription.

Analogs

The drug has analogs in the form of drops. They are usually intended for the treatment of eye pathologies of varying severity, but can be used in an unconventional way, that is, for the treatment of hemangiomas.

Most popular substitutes:

• Arutimol has the same composition as the original product, but comes in the form of drops for topical use. The drug can be applied to the tumor as prescribed by the doctor, in most cases it is used in the same way as the original.
• Okumed is considered one of the safest analogs based on the active component of timolol. The tool is available in the form of eye drops, it can be prescribed to children from the first months of life when a benign neoplasm appears. The treatment regimen does not differ from that used when prescribing the original remedy.
• Betaxolol in the form of eye drops can also be used as a substitute for hemangioma on the skin. The medicine helps to eliminate the neoplasm or to reduce its size.

The selection of an analogue is made by the doctor after a preliminary examination of the affected area.

Terms, conditions of sale and storage

Dispensing of the medicine in different pharmacies is carried out after the presentation of the prescription form. The maximum storage time is 2 years.

During storage, it is important to avoid direct sunlight on the bottle. After the expiration date, use is prohibited.

Price

The cost of the medicine is affordable, it is about 60-120 rubles. depending on the volume of the bottle and the region of distribution.

Timolol is an effective ophthalmic gel, which is often used in an atypical way to get rid of hemangiomas in children of different ages and adults. The tool does not always help get rid of the neoplasm, but often after using it, its size decreases.

Video about Timolol from hemangioma

Hemangioma treatment. Arutimol / Timolol: