Dorzopt eye drops. Price, instructions for use, analogues, reviews

Dorzopt refers to drugs that are prescribed with increased intraocular pressure. The medication slows down the development of the disease, but is not able to completely eliminate the pathology.

To achieve the best therapeutic effect, eye drops are recommended for use in complex treatment. This article describes the complete instructions for the medicinal product, as well as the price range in Russia.

Forms of release and composition of the drug

Dorzopt is odorless 2% eye drops. They are produced in the form of a transparent and colorless solution, which is placed in an amount of 5 ml in plastic bottles with a dropper.

The therapeutic effect of the drug is provided by the main component - dorzolamide, which normalizes the production of intraocular fluid.

Also the drops include:

• hyethylosis - it is used as a stabilizer for a drug, and the element also creates an invisible thin film, preventing the evaporation of drops from the mucous membrane of the eye;
• mannitol - the component promotes the removal of excess fluid from the tissues of the eye;
• citric acid monohydrate - is a preservative necessary to extend the shelf life of drops;
• benzalkonium chloride - the element has antiseptic properties, as a result, Dorzopt prevents the development of infectious eye diseases;
• sodium hydroxide - the component allows you to extend the shelf life of the medication;
• distilled water - is a binder component, and also gives the drops the desired concentration.

The therapeutic effect of the drug is provided due to the correctly selected proportions of the main and auxiliary elements.

Pharmacological properties

Dorzopt refers to antiglaucoma drugs. The medication delays the production of intraocular fluid, resulting in a decrease in intraocular pressure.

Pharmacodynamics and pharmacokinetics

Dorzopt - eye drops, the price of which varies from the region of purchase of the drug. They are allowed to be used only as directed by an ophthalmologist.

The multicomponent composition of the drug provides the following medicinal effects:

• the main element slows down the production of intraocular fluid, which causes an increase in intraocular pressure;
• also the active substance helps to slow down the transfer of fluid in the eye tissues;
• additionally, drops protect the mucous membrane of the eyes from penetration and development of infection (fungus and viruses);
• Once in the eye tissues, the drops affect the eye muscles, resulting in a temporary restoration of vision clarity.

The use of the drug does not impair the quality of vision, does not provoke pupil constriction, and does not cause photophobia. The components of the drug penetrate to the eye tissues mainly through the cornea (a small part is absorbed through the edge of the cornea and sclera). Further, an insignificant part penetrates into the circulatory system and accumulates in erythrocytes.

The effect of the drug is noted 30 minutes after instillation and can persist up to 10 hours after the procedure. The components that make up the drops are excreted mainly in the urine (unchanged).

The period of elimination of the drug from the body, after the end of the course of treatment, can be up to 4 months. The duration of cleansing the body from the medication is due to the gradual release of the main component of the drug from erythrocytes.

Indications for use

Dorzopt eye drops can be prescribed by an ophthalmologist in the following cases:

Pathology name	Brief description of the disease
Open-angle glaucoma (primary or secondary)	Pathology is characterized by an increase in intraocular pressure with impaired vision quality. It develops as a result of a violation of the outflow and the formation of intraocular fluid
Pseudoexfoliative glaucoma	It is a type of open-angle glaucoma, accompanied by the formation of white deposits in the eye tissues (mainly in the lens and ciliary body).
Ophthalmic hypertension	An increase in intraocular pressure is noted as a result of stress, endocrine diseases, or as a result of taking medications.

Also, drops are prescribed by a specialist for other eye pathologies, which are accompanied by an increase in intraocular pressure.

Contraindications

Dorzopt - eye drops, the price of which, according to buyers, is somewhat overpriced.

It is forbidden to use them in the presence of the following deviations:

• kidney disease. Drops have a diuretic effect, as a result of their use causes an increase in the load on the kidneys;
• hyperchloremic acidosis. Pathology is manifested by a violation of the composition of the blood as a result of the accumulation of acidic products in the plasma. The disease is caused by a metabolic disorder in tissues;
• intolerance or allergic reaction to any of the components that make up the drops;
• the presence of conjunctivitis (especially in severe form). Due to a decrease in the production of intraocular fluid, complications from the disease may develop;
• the presence of trauma or swelling on the eyelids;
• violation of the quality of vision for an unexplained reason;
• increased secretion of fluid from the lacrimal canals. As a result, the drug will be washed out without having time to provide a therapeutic effect;
• the presence of inflammatory processes in the eye tissues;
• period of pregnancy. The components of the drug can cause the development of fetal malformations (not proven);
• lactation. The main component enters the bloodstream and can pass into breast milk. As a result, a significant decrease in intraocular pressure in a child is possible with a subsequent deterioration in vision;
• a recent heart attack or the presence of pathologies in the cardiovascular system in severe form;
• asthma and other pathologies in the pulmonary system in severe form.

Drops are not recommended for use after surgery to eliminate glaucoma, as they can provoke retinal detachment and a strong decrease in intraocular pressure.

There are also conditional contraindications to the use of the drug among them:

• violation of the liver. This contraindication is considered conditional, since the auxiliary components may have a slight effect on the functioning of the liver;
• diabetes. The disease is accompanied by a violation of the composition of the blood, and there is also an increase in the load on the kidneys. The dosage of the drug depends on the severity of the disease;
• the presence of pathological abnormalities in the cornea. Depending on the type of disease, the specialist determines the possibility of using drops;
• advanced age (over 60 years old). The course should be prescribed only by a specialist, since it is required to take into account the general condition of the patient.

If there are conditional contraindications, the doctor makes an individual selection of the course of therapy. It is important if the use of drops is carried out ignoring contraindications, then not only loss of vision is possible, but also a deterioration in general well-being.

At what age can the drug be used?

Dorzopt eye drops cannot be used in the treatment of children under 18 years of age. Until this age, the formation of organs and systems occurs, the use of drops can provoke not only a constant decrease in intraocular pressure, but also cause a deterioration in the quality of vision due to the development of deformities in eye tissues.

Instructions for use, dosage

Dorzopt is required to be used only as directed by a doctor in compliance with the dosage and course, which are indicated in instructions (included in the package with eye drops), provided that an individual course is not prescribed therapy. Also, the nuances of using the drug can be checked with the pharmacist along with the price.

Dorzopt drops are required to use 1 drop in the affected eye with a multiplicity of 3 times within 24 hours. If a specialist has prescribed a combination treatment, using additional drops, then the interval between instillation of drugs must be observed, at least 15 minutes.

The frequency of instillation is also reduced to 2 times a day. The duration of the course is 7 days. If there is no result, the possibility of extending the course is discussed with the ophthalmologist.

The effectiveness of treatment depends not only on compliance with the dosage and duration the use of drops, but also on the correctness of the manipulation:

1. Before instillation, you must thoroughly wash your hands (preferably with baby or antibacterial soap) and wash your eyes.
2. Further, the patient must take a recumbent position. The gaze is advised to concentrate on the ceiling.
3. Shake the bottle with drops, remove the cap.
4. Then, with the fingers of one river, you should pull the lower eyelid, with the other hand press on the bottle, dispensing the solution 1 drop into the "pocket" between the lower eyelid and the eyeball. Let go of the lower eyelid. When instilling the dropper dispenser, it should not come into contact with the tissues of the eye.
5. After that, it is advisable not to close your eyes for about 20-30 seconds. It is not recommended to blink during this period of time.
6. Next, you need to close your eyes (do not close your eyes) and make a circular rotation of the pupil. In this case, it is necessary to clamp the lacrimal channels with the index fingers so that the drug does not penetrate into it. Thanks to these actions, the drug is evenly distributed and penetrates into the necessary tissues of the eye.
7. Lie down after the end of the manipulations for about 5-10 minutes.

After the completion of the procedures, the drops must be closed with a cap. It is forbidden to leave the bottle open or touch the dropper dispenser with your hands, as it is possible for germs and dirt to get into the solution. It is important that if the patient wears contact lenses, then it is recommended to replace them with glasses for the period of therapy.

If it is necessary to replace Dorzopt eye drops with another drug, it is necessary to maintain a break between instillations for at least 24 hours.

Side effects

The course of therapy using Dorzopt drops may be accompanied by the manifestation of a negative reaction in the form of:

• temporary burning sensation in the mucous membrane of the eyes after instillation of the solution. The feeling of discomfort disappears approximately 15 minutes after the manipulation. If the negative reaction persists or the burning sensation intensifies, then an urgent need to rinse the eyes. Further, consultation with a specialist is required, since this reaction may mean an allergic reaction to the drug;
• violation of sensitivity in the eye area, as well as the appearance of "goose bumps" on the skin;
• itching sensation in the eyes. The discomfort should go away on its own in about 15-20 minutes. If it is not an allergic reaction;
• increased lacrimation. An increase in the production of fluid from the lacrimal canal is the body's response to the introduction of foreign substances;
• a temporary decrease in the quality of vision is possible (the solution on the mucous membrane of the eye distorts the perception of the outlines of objects and color);
• irritation and swelling of the tissues of the eyelids. This reaction is predominantly allergic. Therefore, you need to immediately rinse your eyes and take antihistamines;
• development of conjunctivitis. The disease can develop due to infection with drops or be the result of allergies;
• inflammation of the cornea of ​​the eye or other inflammatory reactions of the tissues of the eye. A side effect is typical when contraindications are ignored. An urgent appeal to an ophthalmologist is necessary;
• possible temporary development of photophobia, in rare cases. Passes on its own in about 15 minutes;
• change in corneal thickness or retinal detachment. This reaction is possible if the drug was used after surgery to eliminate glaucoma, without observing the recovery time;
• a significant decrease in intraocular pressure. It is more often observed in the elderly or if the drug was used in childhood;
• a feeling of a bitter taste in the mouth. A side effect occurs if the drug gets into the lacrimal canal;
• nausea, tiredness, or weakness. Effects are possible with an overdose of drops;
• headache. Deviation is possible due to intolerance to the components. Adjustment of therapy may be required;
• exacerbation of kidney disease, including the formation of stones. A side effect is noted when ignoring contraindications;
• change in blood composition. A negative reaction is possible with prolonged use of drops. In rare cases (in severe cases), a blood transfusion may be required;

The most common side effect is an allergic reaction to the ingredients, which can include skin rashes, breathing problems, or a burning sensation or itching in the eyes.

Overdose

Dorzopt - eye drops, the price of which differs depending on the pharmacy and the region. They can harm the body in the event of an overdose or with prolonged use in high doses, as well as if the drug is accidentally taken orally.

In case of an overdose of a solution or prolonged therapy, the following symptoms may occur:

• violation of the water-salt balance as a result of changes in the composition of the blood and the influence of the main component on water metabolism in tissues;
• deterioration in the activity of cells of the nervous system due to a violation of the water-salt balance;
• "Oxidation" of blood. Manifested by severe headaches, shortness of breath, drowsiness;
• breathing disorder;
• increased heart rate, arrhythmia;
• increased dryness of the skin and mucous membranes;
• strong pupil dilation. Expressed in increased photophobia;
• possible convulsions due to a violation of the water-salt balance;
• soreness in the digestive tract (especially in the stomach).

It is also possible to increase the side reactions, which are discussed above. If these symptoms are found, emergency hospitalization of the victim is required. The blood composition is monitored by specialists on a permanent basis.

special instructions

The instruction for Dorzopt eye drops, in addition to contraindications, also contains a list of special instructions for their use:

• if it is not possible to replace contact lenses with glasses, then they should be removed for the period of instillation of the solution. It is possible to put lenses in the eyes no earlier than 15 minutes after the instillation of the product. If you neglect this advice, then the drug will react with the material from which the lenses are made, followed by the release of toxic substances;
• long-term therapy requires periodic monitoring of plasma electrolytes;
• in old age, you can use drops only after consulting a therapist. Moreover, in most cases, the selection of an individual dosage and course is required;
• since the solution can cause temporary visual impairment, drowsiness and headaches, it is prohibited to drive vehicles or perform work requiring special attention during the course of therapy;
• the therapeutic effect of the drug in angle-closure glaucoma is unknown (no studies have been carried out), therefore, it is prohibited to use the drug in this type of pathology;
• it is necessary to carefully monitor the cleanliness of the dropper dispenser, otherwise infection may enter the mucous membrane of the eye;
• it is impossible to abruptly interrupt the treatment, it is advised to reduce the dosage of the medication gradually (discussed with the doctor);
• prolonged use of drops can cause not only an overdose, but also addiction to the main component, as a result of which the therapeutic effect is reduced.

It is important that drops can only be used as directed by an ophthalmologist and after consultation with a therapist.

Drug interactions

When an ophthalmologist prescribes complex treatment, the following nuances of using drops should be taken into account:

• drops cannot be combined with analogues of oral use, since the therapeutic effect of the main component is enhanced and an overdose of the drug may develop;
• Dorzopt cannot be combined with diuretics, as they increase the likelihood of side effects;
• Acetylsalicylic acid and other blood thinning medications can increase the toxicity of the drops.

If the patient takes other medications for the period of prescribing drops, it is important to warn the specialist about this, then the doctor will select compatible analogs.

Analogs

Dorzopt - eye drops, the price of which is high. They can, if necessary, be replaced with budget counterparts. Also, replacement can be made if there is an intolerance or allergic reaction to the components of the drug.

Recommended replacement drugs:

Product name, terms of sale and price	Active substance and its principle of action	Brief instruction
Dorzopt Plus (800 rubles, prescription)	In contrast to the classic version, timolol is included in the composition of the drug, which enhances the therapeutic effect.	The drug contains a large list of side effects (more than the classic version). For therapy, it is necessary to instill 1 drop into the affected eye 1-2 times a day. The duration of treatment is established by a specialist.
Azopt (1000 rubles, prescription)	The main element brinzolamide has a therapeutic effect similar to dorzolamide.	Drops should not be used for liver, kidney pathologies or the presence of angle-closure glaucoma. The drug contains a long list of negative reactions. Therapy consists of instilling 1 drop into the eyes 2 times a day. The duration of the course is selected individually.
Betoptik (500 rubles, prescription)	The active substance betaxolol does not disturb the clarity of vision, promotes a rapid decrease in intraocular pressure, the therapeutic effect lasts for 24 hours.	With pathologies of the heart, diabetes mellitus and in childhood, use is possible only with the permission of a doctor. The course of treatment consists of instilling drops of 1 drop into the affected eye 2 times a day for at least 30 days. Of the side effects, neurosis, insomnia and increased lacrimation are more often noted.
Cosopt (900 rubles, prescription)	The main components of timolol and dorzolamide have a therapeutic effect similar to Dorzopt Plus drops.	The instruction of the drug is similar to Dorzopt Plus drops. It is required to bury the solution 1 drop 2 times a day. The duration of treatment is selected individually.
Xalatan (700 rubles, prescription	The active ingredient latanoprost increases the outflow of fluid from the eye tissues, resulting in a decrease in intraocular pressure.	Drops are not recommended for use in childhood and pregnancy. The therapy may be accompanied by discomfort in the mucous membrane of the eye or an allergic reaction. Drops are recommended to be instilled in 1 drop into the affected eye in the evening. The duration of treatment is established by an ophthalmologist.

Droplets can only be replaced by a specialist. Self-replacement of the drug can lead to a deterioration in well-being.

Terms, conditions of sale and storage

Eye drops must be stored in a temperature range of 2 to 25 degrees. In this case, it is important that no rays of light fall on the solution. And also the drug should not be in the reach of children. This nuance is important to consider, since with accidental oral administration, serious consequences are possible.

If stored properly, sealed drops can be stored for up to 2 years. After the start of use, the shelf life is reduced to 1 month. Dorzopt can only be purchased with a prescription. There is no medication on the free market.

It is important that drops with an expiration date or expired are strictly prohibited.

Price

Dorzopt drops are sold in pharmacies in 2 types of packaging: 1 and 3 bottles in a cardboard box. Depending on the choice of packaging, the cost for the drug can be 800 and 1600 rubles. respectively. In this case, the price range can be from 400 to 800 rubles. and from 1100 to 1600 rubles.

It is recommended to buy eye drops after clarifying the course of admission with a specialist. Since, if long-term therapy is necessary, it is recommended to purchase a triple package of Dorzopt solution. In this case, the price of the product is lower.

Author: Kotlyachkova Svetlana

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