Diazolin tablets recommended for use by adults and children after consultation with a specialist. The price of the drug depends on the dosage, manufacturer and locality in which it is sold.
Record content:
- 1 Forms of release and composition of the drug
- 2 Pharmacological properties
- 3 Pharmacodynamics and pharmacokinetics
- 4 Indications for use
- 5 Contraindications
- 6 At what age can the drug be used?
- 7 Instructions for use, dosage
- 8 Side effects
- 9 Overdose
- 10 special instructions
- 11 Drug interactions
- 12 Analogs
- 13 Terms, conditions of sale and storage
- 14 Price
- 15 Diazolin tablets video
Forms of release and composition of the drug
The pharmacological agent is sold in cardboard packages containing blisters with pills or tablets. The drug has the active ingredient mebhydrolin napisylate and is available in dosages of 50 mg and 100 mg. One box contains 10 tablets.
In addition to the main active ingredient, the tablets contain:
- sucrose;
- starch syrup;
- talc;
- beeswax;
- sunflower oil.
"Diazolin" - tablets, the price of which does not determine their effectiveness, have different concentrations of auxiliary components. Their volume depends on the dosage of the medication and the form of release.
Pharmacological properties
The medication is aimed at eliminating the allergic reactions of the body. After its use, histamine H1 receptors are blocked, which entails the elimination of itching, reduction of bronchial smooth muscle spasm, and decreased production of exudate in the upper and lower respiratory tract ways.
Important! The pharmacological agent has a mild sedative effect, which can lead to excessive drowsiness.
Pharmacodynamics and pharmacokinetics
After using the drug, its absorption into the blood is carried out after 15 minutes. from the gastrointestinal tract. 40 - 60% of the total concentration of the active ingredient is absorbed. The penetration of the active substance through the blood-brain barrier (BBB) does not occur. The maximum concentration of the active substance is reached after 3 to 4 hours.
The BBB is an obstacle that prevents the penetration of toxins and other substances from the capillary blood to the neurons of the central nervous system.
The breakdown of drug residues occurs in the liver. Complete elimination of the medication occurs through the urinary system within 48 hours.
Indications for use
A pharmacological agent is prescribed by a therapist, pediatrician or allergist after the following diagnoses have been made:
- urticaria (urticaria);
- hay fever (allergic reaction to pollen);
- allergic rhinitis;
- atopic dermatitis;
- an allergic reaction to medicines or food;
- allergic conjunctivitis;
- skin rashes that have arisen after an insect bite.
Also, the medication is prescribed for the treatment of allergic bronchial asthma in adults as part of a complex treatment.
In some cases, a pharmacological agent can be used as a prophylaxis allergic reactions in the treatment of acute respiratory diseases in children prone to acute allergic reactions.
Contraindications
Taking medicine is prohibited when:
- hypertrophy of the prostate;
- angle-closure glaucoma;
- disruption of the urinary system;
- peptic ulcer of the gastrointestinal tract;
- aggravated inflammatory diseases of the gastrointestinal tract;
- hypersensitivity to the components that make up the medication;
- pyloric stenosis;
- epilepsy;
- violation of the rhythm of heart contractions;
- pregnancy;
- breastfeeding.
Diazolin tablets can be prescribed if there are contraindications, but only after a thorough examination and under the supervision of a specialist. The price of the medicinal product does not exceed 100 rubles.
It is prohibited to use the medication simultaneously with other antihistamines, alcohol and energy drinks, as this leads to an increase in the pharmacological agent in question.
At what age can the drug be used?
The use of Diazolin is allowed from the age of 3. The medication is prescribed in children's form and contains 50 mg of the active ingredient. At an earlier age, it is recommended to resort to the use of means suitable for the child's body, for example, Zodak drops (we can use it from 6 months).
Instructions for use, dosage
Important! The exact dosage and frequency of administration should be determined by a specialist. Self-treatment can lead to negative consequences.
Age and permissible concentration of active substance:
- 3-5 years - from 50 to 150 mg;
- 5 - 10 years - from 100 to 200 mg;
- over 10 years old - from 100 to 300 mg.
Depending on the severity of the allergic reaction, the tablets can be used 1 to 4 times a day. Excessive consumption of the drug leads to the appearance of adverse reactions. The maximum permissible daily dose for an adult is 600 mg, while a single dosage should not exceed 300 mg.
It is recommended to take the medication after a meal. To quickly dissolve tablets or dragees, you should drink them with a sufficient amount of liquid. The duration of therapy should not exceed 5 days; in the absence of the desired result, it is recommended to consult a specialist to change the treatment tactics.
Important! In the presence of acute allergic manifestations, the use of tablets can be carried out regardless of food consumption.
Side effects
"Diazolin" - tablets, the price of which is relatively low, which has a large list of possible negative manifestations.
| Organ system | Negative manifestations |
| Digestive system | Drying of the mucous membranes of the oral cavity, heartburn, diarrhea, excessive gas formation, belching and other signs of irritation of the mucous membranes of the stomach and intestines. |
| Central and peripheral nervous system | Dizziness, excessive fatigue, tremors of the limbs, drowsiness, loss of consciousness and paresthesia. |
| Hematopoietic system | A decrease in the concentration of neutrophils in the blood and a sharp decrease in the concentration of leukocytes. |
| urinary system | Violation of the process of excretion of urine, which leads to an increase in the level of intoxication and exacerbation of other pathological symptoms. |
Subject to the recommendations of a specialist, the negative manifestations from the use of an antihistamine are minimal.
Overdose
Important! When using an excessive amount of the drug, disturbances in the work of internal organs are possible.
Negative manifestations arising from an overdose of an antihistamine:
- mental retardation or stupor;
- hallucinations and confusion;
- spontaneous and inappropriate actions;
- hyperexcitability and increased irritability;
- obsessive states;
- tremors of the limbs or the whole body;
- bouts of nausea;
- vomit;
- stomach cramps;
- bleeding in the organs of the gastrointestinal tract.
The severity of symptoms depends on the dosage of the drug taken and the individual characteristics of the organism. In children, signs of overuse of the drug are more pronounced. In persons suffering from renal or hepatic insufficiency, signs of overdose can be especially acute even when taking a low dose of the drug.
Signs of overdose can be noted when using the normal dose of the drug at the same time as other sedatives and antihistamines, or alcohol-containing drinks. When using Diazolin in parallel with antipsychotics, there may be signs of depression of the central nervous system.
If there are signs of an overdose, it is recommended to rinse the stomach, call an ambulance and bring the emotional state of the person who took the medication back to normal. In the case of obsessive states or panic attacks, it is recommended to explain to the person that there is no threat to his life and health.
With pronounced signs of excessive consumption of a pharmacological agent, it is recommended to resort to the use of activated charcoal or another drug aimed at removing toxins from organism. In some cases, diuretics are required to reduce the level of intoxication.
In the event of signs of respiratory failure or angina pectoris, you must immediately call a specialist. While waiting for the doctor, it is recommended to ventilate the premises and carry out wet cleaning. Cool and humid air helps to improve the condition.
Important! Untimely call of a specialist and lack of first aid can lead to irreversible consequences and death.
special instructions
With prolonged use of a pharmacological agent, the risk of the negative manifestations described above increases. In this regard, the use of the drug is not indicated in the treatment of chronic diseases caused by sensitivity to allergens.
The use of the medication during pregnancy is contraindicated, but in some cases, a specialist may prescribe Diazolin in the last weeks of pregnancy, provided that the positive effect of the pills outweighs the possible risk to the mother and fetus.
In case of disruption of the urinary system and liver, the drug should be taken exclusively under the supervision of a specialist.
When breastfeeding, taking the medication is not recommended, since the active substances penetrate into the mother's milk. But if necessary, the doctor may prescribe an antihistamine if the risk to the mother and baby does not outweigh the potential benefit. During the period of therapy, the woman and the baby should be under the supervision of a specialist.
The medication is forbidden to be used for the treatment of people with diabetes mellitus, since the composition of the pills and tablets contains sugar. Taking an antihistamine can affect blood glucose levels.
During the period of treatment with an antihistamine, it is recommended to stop driving. It is also recommended to exclude any activity that requires a high concentration of attention.
Drug interactions
The interaction of the active components of the antihistamine with other drugs has not been recorded. An exception is medications with sedative and antiallergic effects. Their use during the period of Diazolin therapy should be excluded.
Important! When using any medications, you should inform about them when contacting a specialist. Some drugs require a decrease in the concentration of diazolin during therapy.
Analogs
"Diazolin" - tablets (their price may differ in different pharmacies), which have no analogues, identical in composition. But you can replace an antihistamine with a medicine similar in its effect on the body.
| A medication similar in its action | Description |
| Desloratadine | A tool aimed at eliminating the signs of an allergic reaction. It is a blocker of H1 receptors. It has antihistamine and antipruritic effects. There is a form of release for children and adults. Approved for use from 2 years of age as prescribed by a specialist. The approximate cost is 120 rubles. |
| Ketotifen | Antiallergic drug aimed at reducing the severity of allergic reactions. After taking the medication, there is a decrease in the production of histamine and stabilization of the cell membrane. Can be used from 3 years old after consultation with a pediatrician. The approximate price is 50 rubles. |
| Claridol | H1 antihistamine receptor blocker. The drug normalizes the permeability of blood vessels, eliminates signs of allergic reactions and eliminates itching from insect bites. You can use a pharmacological agent from 2 years old. The approximate cost in Russia is 162 rubles. |
| Clarisens | An agent aimed at reducing the production of wide-spectrum histamine. The drug eliminates the negative manifestations of allergies, eliminates pain and reduces the production of mucous secretions. Oral use of the medication is permissible from 2 years old. The average cost is 73 rubles. |
| Desal | The tool has anti-allergic and anti-inflammatory effects. After taking the medication, the receptors that produce excess histamine are blocked. Application under the age of 12 is contraindicated, since the effect on the child's body has been little studied. The approximate price in the territory of the Russian Federation is 212 rubles. |
| Tavegil | A fast acting antiallergic drug aimed at reducing itching and mucus production. The pharmacological agent has a high concentration of the active substance and is approved for use from the age of 12. The approximate cost in Russia is 216 rubles. |
| Suprastin | Broad-spectrum antihistamine. Eliminates allergy symptoms and has an antiemetic effect. The medication can be used for children from 3 years old after consultation with a pediatrician. The approximate cost is 133 rubles. |
Important! It is not recommended to independently replace one antihistamine with another, as this can lead to negative manifestations.
All of these drugs begin to act in the first 30 minutes after administration. The duration of the activity of the active substance is from 3 to 12 hours.
Terms, conditions of sale and storage
"Diazolin" - tablets, the price of which is different, depending on the dosage. They are dispensed in pharmacy chains without a prescription from a doctor.
You can store the pharmacological agent in the form of tablets for 36 months at a temperature not exceeding 25 degrees. The package with the medication should not come into contact with moisture and direct sunlight. Dragee storage period is 42 months.
It is forbidden to use an antihistamine after the expiration date, as the effect on the body can be unpredictable. The production date and storage time are indicated on the packaging and blister with tablets.
Price
The cost of a medicinal product may vary depending on the manufacturer, dosage and locality in which it is sold. On average in Russia, the cost of one package ranges from 50 to 80 rubles. In Moscow, you can buy tablets with a dosage of 50 mg for 33 rubles.
Interesting fact! The cheapest drug is produced by Pharmstandard-Ufa Vitamin Plant, its cost does not exceed 30 rubles. One package contains 10 pills with a dosage of 0.1 g. Despite the low cost, the effectiveness of the drug is high.
Diazolin tablets are an effective remedy with a low price, allowing you to get rid of the signs of allergies, but having a wide range of negative manifestations and contraindications. Before using it, you need to consult with your therapist or allergist.
Diazolin tablets video
Indications for the use of Diazolin:
