Ciprolet eye drops. Price, instructions for use, indications, analogues, reviews

Tsiprolet is a medicine, intended for instillation of eyes in the presence of a microbial lesion. The drug is an affordable price and a wide range of applications.

Forms of release and composition of the drug

This drug is made in the form of eye drops. The active substance of the drug is ciprofloxacin hydrochloride.

Auxiliary composition:

• 0.5 mg disodium salt of ethylenediaminetetraacetic acid;
• 9 mg sodium chloride;
• benzalkonium chloride solution with an effective concentration of 50%;
• hydrochloric acid;
• injection water.

The drug is poured into plastic bottles equipped with a dropper dispenser. Each vial is packed in a separate cardboard container and is accompanied by an insert instruction.

The volume of the bottle is 5 ml.

Pharmacological properties

Tsiprolet - eye drops (the price of the drug is in the budget segment), which have broad antimicrobial activity and belong to the category of fluoroquinolone compounds.

The main component has a depressing effect on the DNA cells of pathogenic microorganisms, while disrupting their further division. The process leads to disruption of the action of bacteria and causes their death.

The drug has a detrimental effect on gram-negative pathogenic microflora. In relation to gram-positive microorganisms, the drug has a negative effect only during the period of cell division. This process is due to the fact that at a given time period the bacterial flora lacks DNA gyrase.

When using the drug, there is no development of resistance in pathogens that show resistance to other groups of antibiotics - penicillins, aminoglycosides, cephalosporins.

The drug is highly effective against the following bacteria:

• staphylococcal pathogen;
• colibacillus;
• klebsiella;
• enterobacteria;
• proteas;
• vibrios;
• diplococci;
• serration;
• the causative agent of hemophilic infection;
• morganella;
• Yersinia;
• hafnium;
• causative agent of capylobacteriosis;
• lsiteria;
• mycobacteria;
• chlamydia;
• streptococcus.

Varieties of staphylococcal pathogens resistant to methicillin are also not susceptible to the action of the drug. Moderate activity of drops is noted when they act on fecal varieties of enterobacteria, as well as streptococci responsible for the development of pneumonia.

The medication is not effective against pale treponema.

The development of resistance to antibiotic action takes an extremely long time, since pathogenic microorganisms do not possess enzymes that can neutralize the action of the drug.

Pharmacodynamics and pharmacokinetics

After using the medication, the maximum accumulation level of active substances is 5 ng / ml. Average values ​​vary within 2.5 ng / ml. When used, the drug is capable of exerting a systemic effect.

The components of the solution are excreted mainly through the intestines. In this case, the main substance practically does not undergo metabolic processes and leaves the body in an unchanged form (more than 50%). About 10% of the drug is excreted as metabolites. The drug can pass into breast milk.

Indications for use

Tsiprolet - eye drops (the price of a solution is affordable for most patients), which are used in the development of infectious and inflammatory processes in the eye area.

Indications:

• acute and subacute form of conjunctival lesions;
• the presence of blepharitis, blepharoconjunctival infection;
• the presence of ulcers located in the cornea of ​​the eye and having a bacterial origin;
• bacterial forms of keratitis and keratoconjunctivitis;
• chronic course of dacryocystitis and meibomitis.

The tool is also used as a prophylaxis before eye surgery. The solution can be used in the treatment of infectious complications caused by surgical operations. Treatment with the drug is also carried out after injury to the eyes or the ingress of foreign bodies into them.

Contraindications

The tool has some restrictions on its use, since the action of the active ingredient can lead to a deterioration in the patient's condition.

Contraindications:

• viral form of keratitis;
• During pregnancy and breastfeeding;
• allergic reactions to the components that make up the drops;
• childhood.

With extreme caution, the agent is allowed to be used for atherosclerotic lesions of the vessels of the brain, in the presence of seizures, as well as in case of impaired blood circulation in the brain.

At what age can the drug be used?

The drug is allowed to be prescribed to children who have reached 1 year of age. In this case, treatment with a solution is carried out only under the supervision of the attending ophthalmologist.

Instructions for use, dosage

The medicine is intended for topical use. In mild and moderate forms of infection, 1-2 drops of medication are prescribed in each eye / conjunctival sac. Use the solution every 4 hours. With a severe course of the pathological process, the medicine should be applied every hour.

With good tolerance of the solution and high therapeutic efficacy, it is recommended to gradually reduce the dosage.

In the presence of an ulcerative lesion that has a bacterial nature of origin, 1 drop of medication is prescribed every 15 minutes. Apply the drug according to this scheme for 6 hours.

After this period of time, the medicine must be used according to a different scheme: 1 drop of solution every half hour. Starting from the second day, 1 drop of the drug is prescribed every hour. From 3 days to 2 weeks, the drug is used in a dosage of 1 drop every 4 hours.

No dosage adjustment is required in elderly patients. Studies in patients with impaired renal function to determine the occurrence of dose-related adverse reactions have not been conducted.

In the absence of a therapeutic effect, therapy can be continued after a preliminary consultation with an ophthalmologist.

Side effects

The solution can lead to the occurrence of negative reactions, the development of which is due to the action of the main substance or the physiological characteristics of the patient.

Side effects:

• On the part of the visual organs: burning sensation, itching, redness in the area of ​​the eye. Rarely, the use of a solution can lead to increased sensitivity to light, tearing, and the development of puffiness. The drug can cause a decrease in visual function, as well as lead to the sensation of a foreign object in the eye. The formation of white crystalline deposits in patients with ulcerative formations is also noted. In extremely rare cases, a medication can provoke the development of keratitis, keratopathy, and also lead to the formation of infiltrations.
• Other reactions: allergic manifestations, the development of nausea. It is extremely rare to experience discomfort in the mouth, as well as develop superinfections.

If side effects occur, including reactions not listed in the official instructions, it is recommended to discontinue therapy and seek advice from an attending ophthalmologist.

Overdose

To date, there are no data on the development of any negative reactions when the dosage is exceeded.

In case of accidental ingestion of the drug, the following symptoms may occur:

• nausea and vomiting;
• diarrheal syndrome;
• headaches;
• fainting;
• anxiety.

In case of accidental drug poisoning, a large amount of liquid is recommended. It is also necessary to create an acidic urine reaction, which will prevent the development of crystalluria.

special instructions

Tsiprolet belongs to local ophthalmic preparations. At the same time, the cost of the medication is not a factor that affects the therapeutic effect of the eye drops.

It is forbidden to use the drug in any other way, except for the local one. In this case, the solution should be injected only into the conjunctival sac, avoiding getting into the anterior chamber of the eye.

When using the product, it should be borne in mind that there is a high probability of developing an infectious lesion due to the action of microorganisms resistant to solution. The process is associated with the risks of developing a rhinopharyngeal passage. To prevent the onset of the disease, it is recommended to undergo constant examinations by an ophthalmologist.

The medicine must be canceled at the first sign of allergic reactions.

It is recommended to remove contact lenses before using the solution, as the drug can affect the color and structure of ophthalmic devices.

This process is associated with the action of auxiliary components. It is allowed to put the lenses back on after 15-20 minutes. after applying the product. It is recommended to completely abandon contact lenses in the presence of an infectious eye lesion.

When using other ophthalmic agents, the interval between their use should be at least 5-10 minutes.

After taking the medicine, it is necessary to keep the eyelids open for at least 2-3 minutes. After using the solution, it is recommended to pinch the nasolacrimal canal with your finger, which will avoid the spread of the agent outside the conjunctiva.

The additive benzalkonium chloride can cause irritation. A similar effect is observed in patients with overdried eye membranes or in the presence of lesions in the stratum corneum. If a negative action develops, you should contact the treating specialist.

According to laboratory studies on mice, the drip solution does not affect the human reproductive system. However, during pregnancy, it is recommended to refrain from using the product. Its use is possible only in consultation with a specialist, taking into account the potential benefits and possible risks.

The solution may interfere with visual function, therefore it is recommended to exercise great care in the period of their use when driving a car or during work that requires high psychomotor reactions.

Drug interactions

The simultaneous use of an ophthalmic solution and drugs belonging to the group of fluoroquinolones, it is possible to increase the concentration of theophylline. At the same time, the development of a negative effect was noted after applying a single dose.

In some cases, signs of cardiovascular pathologies, fainting, tremors, and the development of swelling in the face and pharynx were observed. In rare cases, such a joint use of funds led to the development of allergic reactions and shortness of breath.

The drug affects the metabolic activity of caffeine. The combined appointment of drops and anticoagulants can lead to an enhanced effect of the second group of drugs.

The combined use of the solution and warfarin, as well as its derivatives, can enhance the effect of the second group of substances. The combination of the drug with cyclosporine can lead to an increase in the concentration of creatinine. The drug must not be used simultaneously with alkaline solutions.

Analogs

Tsiprolet - eye drops (the price of a medicine is not a criterion for prescribing analogs), which in some patients can lead to the development of hypersensitivity reactions. In this case, it is recommended to replace the drug with a similar drug.

Analogs:

• Quintor. This drug is a representative of the fluoroquinolone group of drugs and is produced in the form of an ophthalmic solution for topical use. Its active ingredient is ciprofloxacin. The drug has other dosage forms - injection solution, capsules for oral administration. Quintor has a bactericidal and antibacterial effect, which is aimed at suppressing gram-positive and gram-negative pathogenic microflora. Indications for appointment: infectious processes occurring in the respiratory and urinary tract, severe course of infectious processes in the ENT organs, infectious damage to the joints, bones and skin. Local indications are: blepharitis, various forms of conjunctivitis, dacryocystitis, meibomitis. The tool is also effective in preventing the development of infections after trauma or surgery. The daily dosage is 1-2 drops in each eye. The procedure is carried out every 4 hours. the solution is contraindicated in pregnancy, as well as in adolescence up to 15 years. Cost - from 255 rubles.
• Ciloxan. This ophthalmic drug belongs to the category of fluoroquinolones, made on the basis of ciprofloxacin, an active substance. It has the form of eye drops and exhibits pronounced bactericidal and antibacterial properties aimed at suppressing pathogenic microorganisms. The drug is effective against most gram-negative and gram-positive microflora. Indications for prescribing the drug are bacterial forms of conjunctivitis and the presence of ulcers in the cornea of ​​the eye. Restrictions on the use of the medication: age up to 12 years, pregnancy. The dosage depends on the form of the lesion and is set individually. The course of treatment should not exceed 7 days. The medication is subject to prescription from pharmacies. The cost of the medicine ranges from 130 to 270 rubles. for the bottle.
• Tsipromed. This medicine is produced at a pharmaceutical plant in India. It comes in the form of an eye instillation solution, the main component of which is ciprofloxacin. The medicine has a bactericidal and broad antibacterial effect aimed at eliminating gram-positive and gram-negative microflora. The drug is used in the treatment of infectious diseases occurring in the eye area. Indications: conjunctival lesion, anterior form of uveitis, keratitis, inflammation in the eyelid region (blepharitis), the presence of dacryocystitis. Ophthalmic solution can also be prescribed for prophylaxis in the period before or after surgery. Contraindications to the use of the medication are allergic reactions, children under 1 year of age, pregnancy. The dosage is calculated individually, based on the form of the disease. Dispensing from pharmacies is by prescription. The price of drops starts at 107 rubles.

Tsiprolet - eye drops (the price of analogs may differ significantly from the main drug), which should be replaced with identical drugs only after prior consultation with the attending physician an ophthalmologist.

Terms, conditions of sale and storage

• The drug should be stored in a dry, dark place at temperatures up to 25 ⁰C.
• The shelf life of the medicine is 2 years from the date of manufacture.
• Do not use the solution after the expiry date of the expiration date on the package. After opening the bottle, drops are allowed to be used for 1 month.
• Eye drops are dispensed with a doctor's prescription.

Price

You can purchase a drip solution at a different cost, which depends on the area and region of sale.

Region and region of sale	Dosage form / dosage	Price
Moscow, Moscow region	Drops, 5 ml	RUB 32-65
St. Petersburg	Drops, 5 ml	34-95 rubles
Saint Petersburg (suburbs)	Tablets, 250 mg	RUB 45-66
Leningrad region	Drops, 5 ml	RUB 37-94
Novgorod region	Injection solution, 100 ml	RUB 50-85

Before using eye drops, you must carefully study the instructions for use of Tsiprolet and consult with your attending ophthalmologist or pharmacist. Additionally, you should read the reviews of patients who have taken the drug. You can find out the exact price and purchase a medication at any pharmacy network located in the patient's place of residence.

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