Alpha Normix and analogues are cheaper. List, price, reviews

Alpha Normix is ​​Italian antibiotic with a large spectrum of action. The main element of the drug (rifaximin) disrupts the vital activity of bacteria (under its influence, they die), reduces the amount of toxins (they are produced by bacteria in the process of vital activity), and also prevents the development inflammation.

This medication, like its analogues, is prescribed to eliminate bacterial infection in the digestive tract. The disadvantage of an antibiotic is its overpriced, so doctors often prescribe cheaper substitutes.

Domestic and imported analogues of the product

Alpha Normix and analogues (cheaper or more expensive) can only be prescribed by a doctor. It is strictly forbidden to use these drugs on your own, since antibiotics have a detrimental effect not only on pathogenic, but also on "useful" microflora.

The choice of a substitute is carried out by the attending specialist, taking into account the correspondence of the indications and after the exclusion of contraindications in the patient. Further, medications with a similar therapeutic effect and with a brief description of the instructions are considered, for the convenience of comparing the original with analogues.

Azithromycin

Alfa Normix and analogs (drugs are mainly of domestic production are cheaper) based on azithromycin (as a substitute of the same name Azithromycin) have an extended range of therapeutic actions. An analogue is produced in the form of tablets, capsules and powder for suspension design (the drug manufacturers are Russia, India, Ukraine, as well as Spain and China).

The main component of the substitute suppresses the vital activity of bacteria, which leads to their death. The advantage of the antibiotic is the preservation of the antibacterial effect in the body for 5-7 days after the end of the course. The range of prescriptions for Azithromycin is wider than that of the original.

For ease of comparison, the points of indication for both antibiotics are listed below:

When Azithromycin is prescribed

Indications for Alpha Normix

the presence of infection in the lungs and ENT organs (bronchitis, sinusitis, otitis media); pathologies of a bacterial nature in the organs of the genitourinary system; dermatological diseases of an infectious nature; borreliosis (first stage after infection). The infection is transmitted by a tick bite; in case of damage to the tissues of the stomach or duodenum with the bacterium Helicobacter pylori.

SIBR. Pathology is characterized by the migration of "beneficial" bacteria from the large intestine to the small intestine; the presence of diverticulums (hernial protrusions) in the colon; diarrhea caused by a change in the region of residence. For example, moving, business trip or vacation to places with different climatic conditions; acute infections of the digestive tract; hepatic encephalopathy. The disease is caused by neuromuscular or mental disorders and manifests itself in patients with liver failure; the presence of chronic intestinal inflammation; to prevent the development of infection in the digestive tract after surgery on the digestive tract.

That is, Azithromycin is used to eliminate bacterial infection throughout the body, and not only in the digestive tract, like the antibiotic Alpha Normix. There are no general drug destinations. Before starting to use the drugs, the doctor must first rule out contraindications, which also have differences due to the difference in the main components of the drugs.

Comparative table of contraindications:

Bans of Azithromycin	Contraindications Alpha Normix	General prohibitions
When the use of antibiotics is completely banned
disruption of kidney function in acute form;  severe liver pathology; weight up to 5 kg for suspension powder; weight up to 45 kg for capsules and tablets.	the patient has intestinal obstruction; diagnosing intestinal ulcers in a patient; severe diarrhea accompanied by fever; age up to 12 years, for both forms of release.	intolerance to the constituent antibiotics; carrying a child. Since the active substance (typical for both antibiotics) penetrates the fetus through the placental barrier.
When to use antibiotics, but under special supervision
myasthenia gravis. The disease is manifested by rapid fatigue of muscle tissue; violation of water and electrolyte balance (especially with a deficiency of potassium and sodium); with bradycardia. Pathology is manifested by a pathologically small number of heart contractions per minute; severe heart failure; the presence of arrhythmia in the patient (violation of the rhythm of heart contractions is manifested).	No individual restrictions	Mild to moderate liver and kidney pathologies

When breastfeeding, antibiotics are allowed, but subject to the transfer of the baby (for the period of treatment) to artificial feeding.

The dosage of Azithromycin, like Alpha Normix, is set by the doctor according to the general condition of the patient and the purpose of using the antibiotic. The average range of drug use is 3-7 days.

When undergoing a course of therapy with these medicines, doctors and patients describe the following symptoms of side effects:

Side effects of Azithromycin	Negative reaction to Alpha Normix	Common side effects
decrease in the quality of vision; fainting; decreased susceptibility of the patient to external stimuli; fast fatiguability; the development of seizures; change or lack of smell; strong weight loss; inflammation of the gastric mucosa; increasing the concentration of urea in the body; yellowness of the epidermis due to impaired liver function. In extremely rare cases, liver tissue necrosis develops; development of the inflammatory process in the kidneys; exacerbation of dermatological pathologies; violation of the rhythm of heart contractions; decrease in pressure; tinnitus and hearing loss.	increased blood pressure; the release of cold sweats; heartburn; decreased appetite; dehydration; ear pain; cough; disruption of the liver; violation of urine output from the body; itching in the genitals; violation of menstruation; runny or stuffy nose (no runny nose).	allergy symptoms from rashes to tissue edema; headache; palpitations; dizziness; violation of taste or complete loss of taste; breathing disorder; the development of fever; diarrhea, can be replaced by constipation and vice versa; nausea, in rare cases vomiting occurs; pain in the stomach; deficiency of lymphocytes and leukocytes in the blood, as well as a decrease in the amount of iron and platelets; increased drowsiness or vice versa - the development of insomnia; increased excitability, nervousness, aggression; burning or tingling sensation in the limbs; accumulation of gas in the intestines; the presence of blood in the feces; the development of an infection (mainly fungal) in the vagina, on the skin or in the mouth; the appearance of joint and muscle pain.

In case of poisoning with Azithromycin, patients experienced profuse vomiting, diarrhea and a sharp decrease in hearing. An increase in other side symptoms is not excluded. Treatment is recommended for emerging symptoms. Similarly, an overdose manifests itself and is stopped when using the original.

Both antibiotics can only be purchased with a prescription. It is typical for all forms of release.

It is not recommended to combine azithromycin and Alfa Normix with alcohol, since alcohol increases the load on the liver, as a result, the symptoms of adverse reactions intensify. Additionally, it should be borne in mind that the analogue and the original cannot be used in conjunction with oral contraceptives, since the antibiotic greatly reduces their effect.

Amoxicillin

Analogue Amoxicillin (manufacturers Russia, Serbia and the Netherlands) is produced in the form of tablets, capsules and powder. The leading element of the antibiotic (amoxicillin) has a destructive effect on bacteria (has a wide spectrum). The action of the substitute is similar to the drug Alpha Normix, but the cost of Amoxicillin is several times cheaper.

The list of indications for the appointment of Amoxicillin includes:

• respiratory infections (bronchitis, pneumonia;
• infectious and inflammatory kidney damage;
• the presence of infection or inflammation in the organs of the genitourinary system (bladder, genitals, or urethra);
• diseases of the digestive tract of an infectious and inflammatory nature;
• infectious lesion of the epidermis;
• borreliosis from the initial stage;
• meningitis. The disease is manifested by inflammation of the lining of the brain;
• salmonellosis;
• in case of "decay" of tissues as a result of a running infectious and inflammatory process;
• to prevent the development of endocarditis (the inflammatory process affects the inner lining of the heart).

Also, Amoxicillin can be prescribed in combination with Metronidazole (antibiotic) for inflammation of the mucous membranes, stomach and duodenal ulcers (if the pathology is caused by the Helicobacter pylori bacterium). For comparison, Alfa Normix is ​​prescribed only to eliminate bacterial infections in the digestive tract. Contraindications to the use of Amoxicillin also differ.

When you can not use Amoxicillin	Contraindications Alpha Normix	General prohibitions
the presence of infectious pathologies of the digestive tract in a severe form, especially when accompanied by a disease with vomiting or diarrhea; Infectious mononucleosis. This is an acute viral disease that affects the lymph nodes, spleen, liver, and also disrupts the composition of the blood; lymphocytic leukemia. The disease is malignant in nature and is manifested by an increased content of lymphocytes in the blood and bone marrow; the presence of allergic diathesis or allergic rhinitis in the patient; detection of a viral infection in a patient; bronchial asthma; age up to 2 years for a powder for preparing a suspension; acute liver pathology; age up to 5 years for capsules; age up to 10 years for tablets.	intestinal obstruction; the patient has an ulcer in the intestine; fever and bloody stools; impaired renal function; age up to 12 years (for tablets and granules).	allergy to elements of medicines; carrying a child.

When taking Amoxicillin, as with the use of an analogue, a temporary cessation of breastfeeding is required. From the data in the table it follows that Amoxicillin stands out from the original not only with a large list of indications, but also contraindications.

The dosage of Amoxicillin is selected according to the type of dosage form, the purpose of use and the general condition of the patient. The duration of treatment can be from 5 to 12 days (Alpha Normix can be used for no more than 7 days). The list of adverse reactions, when using an analogue, is also large (like the original).

When using Amoxicillin, the patient may experience:

• allergy symptoms. For example, Quincke's edema, conjunctivitis, urticaria and others;
• exacerbation of chronic pathologies;
• exacerbation of an infectious disease if the bacterium is not sensitive to this antibiotic;
• disorder of coordination of movements;
• depression;
• dizziness and sleep disturbance;
• the development of seizures;
• joint pain;
• vomit;
• constipation followed by diarrhea;
• development of stomatitis;
• violation of the activity of the liver, as well as the kidneys;
• stomach ache.

In case of an accidental overdose of Amoxicillin, side effects increase. If gastric lavage is not effective, and the patient is in serious condition, then hardware purification of the blood is necessary. Further, therapy is prescribed according to the symptoms that appear.

You can buy Amoxicillin only with a prescription. It is typical for all dosage forms of release.

Important. Amoxicillin is recommended to be used in conjunction with clavulanic acid (especially in childhood) and metronidazole, which enhance the therapeutic properties of the antibiotic.

Ampicillin

Alpha Normix and analogues are categorically impossible to use for longer than the course indicated by the doctor, since there is a sharp increase in the symptoms of adverse reactions, and a general deterioration in health develops in sick.

Ampicillin substitute is no exception to these rules. The active element of the antibiotic (ampicillin) has a detrimental effect on bacteria from a wide range.

You can buy an analog in the form:

• capsules;
• tablets;
• dragee (for suspension preparation);
• powder (to create a solution for injection).

The list of indications for the appointment of Ampicillin is much broader when compared with Alpha Normix.

The analogue is used in the following cases:

• sinusitis (inflammation of the maxillary sinuses);
• tonsillitis;
• development of the inflammatory process in the outer, middle or inner ear;
• inflammation of the bronchi;
• purulent tissue inflammation;
• pneumonia;
• the presence of an infection in the urinary tract;
• development of the inflammatory process in the kidneys;
• infectious inflammation of the bile ducts;
• inflammation of the cervix;
• the presence of infectious pathologies in the genitals;
• the development of chlamydia in pregnant women;
• infectious dermatological diseases;
• salmonellosis, dysentery, typhoid fever;
• the development of inflammatory processes in the abdominal region;
• the presence of inflammation in the tissues of the heart;
• inflammation of the lining of the brain;
• the development of inflammatory processes in the connective tissue;
• blood poisoning, accompanied by an inflammatory process.

The advantage of Ampicillin (when compared with Alpha Normix) is not only a wide list of indications, but also a minimal list of contraindications.

Analog cannot be used in the following cases:

• increased susceptibility to antibiotics;
• the patient has lymphocytic leukemia;
• carrying a child;
• Infectious mononucleosis;
• breast-feeding;
• liver failure in acute form;
• age up to 4 years for tablets;
• age up to 1 month for other forms of release.

The rules for the use of Ampicillin (dosage, course) are established by the doctor strictly individually.

When taking the drug, one should take into account the likelihood of developing a negative reaction of the body, which can manifest itself in the form of:

• runny nose, itching, peeling of the epidermis and other symptoms of allergies;
• dysbiosis;
• inflammation of the gastric mucosa;
• violation of taste perception;
• dry mouth;
• the appearance of abdominal pain;
• nausea;
• development of stomatitis;
• diarrhea;
• inflammation of the mucous membranes of the small or large intestine;
• inflammation of the tissues of the tongue;
• development of motor restlessness;
• depression, aggression;
• convulsions, limbs;
• violations of the composition of the blood;
• disorders of the kidneys or liver;
• the development of a fungal infection in the vagina.

When poisoning with Ampicillin, side effects are enhanced. If gastric lavage does not work, then hardware purification of the blood is prescribed. Further, treatment is carried out according to the symptoms that arise.

You can buy an analogue only with a prescription, like Alpha Normix.

Important. Ampicillin categorically cannot be combined with alcohol, since alcoholic beverages increase the severity of side effects, the development of severe poisoning is possible.

Prices

The cost of the antibiotics considered may differ depending on which network of pharmacies the medication was purchased from, as well as the area of ​​sale.

Below for comparison is an overview of the price of the original and analogues:

Antibiotic name	Number of tablets in a package	Price range (RUB)
Alpha Normix	36 pcs.	1600-1690
Azithromycin 250 mg	6 pcs.	140-185
Amoxicillin 250 mg	20 pcs.	55-75
Ampicillin 250 mg	20 pcs.	35-50

Alfa Normix, like its substitutes, is produced not only in tablet form, but for convenience of comparison, the table contains medicines in the form of tablets.

When choosing a cheaper drug, it should be borne in mind that Alfa Normix is ​​a specialized antibiotic (it is used only to eliminate bacteria in the organs of the digestive tract, and analogs have a general effect), therefore, its effectiveness will be higher than the analog.

Video about the drug Alpha Normix

Instructions for use, indications and analogues of Alpha Normix: