Drops, pills and injections Haloperidol - instructions for use, reviews of people and drugs analogues

Haloperidol belongs to the group of drugs of antipsychotic action, created on the basis of the starting material - butyrophenone. For the first time the drug was tested for fitness in the late fifties of the twentieth century in Belgium.

The medical company Jenssen Pharmaceuticals was involved in the tests. This tool is used in the treatment of severe and mild forms of schizophrenic manifestations of .

Also, the drug is effective in manic attacks, delusional state, oligophrenic and alcoholic seizures. Haloperidol is able to prevent hallucinations and mental arousal of .

Dosage forms of the preparation

Haloperidol is available in several forms, depending on the manufacturer and composition.

The most popular types are such drugs: haloperidol-decanoate, haloperidol-richter in tablets and ampoules, haloperidol-ratopharm, haloperidol-acry in the form of tablets and solution, haloperidol-forte.

Haloperidol-decanoate

Haloperidol deanate is an greasy oily solution of in a transparent color. It can also be yellow or light green. The drug is placed in ampoules of dark glass, which should be preserved in contour packs and cardboard tightly closed packages.

The agent, in fact, consists not of pure haloperidol, but of its ether diluted with decanoic acid. Also, the medicine can relieve chronic pain. As auxiliary substances in the composition contains benzyl alcohol, which has an antiseptic effect, and sesame oil.

Haloperidol-Richter

Haloperidol-Richter - is a German solution for the administration of , which has the appearance of a virtually colorless liquid. Also acceptable is a slightly yellowish hue.

Available in ampoules of clear glass and placed in packs. In addition to the main substance, haloperidol, water and lactic acid, which exerts an antimicrobial effect, perform auxiliary functions.

Haloperidol-Richter is also manufactured in tablet form. They are usually white, completely flat, odorless and are engraved on one side. The composition includes potato starch, which is used as a filler of the drug.

Also colloidal silicon dioxide, which is an excellent adsorbent and regenerating agent, magnesium stearate, which acts as an emulsifier, and lactose monohydrate as a food additive.

The amount of haloperidol in the tablets of this company may also be different. Both 1.5 milligrams and 5 milligrams. The visual difference will be the absence of labeling on five milligram tablets.

Haloperidol-ratiopharm

Haloperidol-ratiopharm is an drop for internal use of .They are contained in bottles with special droppers, and the composition of haloperidol does not exceed two milligrams.

In addition to water, the composition includes methyl parahydroxybenzoate and propyl parahydroxybenzoate, which act as preservatives, and lactic acid.

Haloperidol-acry

Haloperidol-acry is also available in two forms. Both solution and tablets have a similar composition with haloperidol-Richter.

Haloperidol-forte

Haloperidol-forte comes in the form of tablets and includes silicium anhydrous colloid for regeneration, white gelatin, talc, starch and lactose.

Pharmacological action

The drug has not only antipsychotic, but also antiemetic effect of .

Haloperidol is also good in tandem with generic anesthetics and those medications that depress the central nervous system.

When the drug enters the body

Haloperidol has a very fast absorption. It is bioavailable about seventy percent. In the blood, it is concentrated to the maximum after three to six hours. Almost the maximum binds itself to proteins in the plasma.

But in tissues it concentrates more than in blood. In the liver, due to the effect of the drug, a metabolic process occurs, but it is not active. The drug is excreted by the kidneys and in the stool.

Indications for use

He is prescribed with psychosis, which is accompanied by delirium, manic attacks, hallucinations and other forms of disorders.

is effective in the treatment of paranoia , in cases where the patient associates himself with another person.

The remedy is also used as a preparatory, before the rapid surgical intervention of in case of emergency.

Contraindications

Refer to the instructions for use, which indicate contraindications to the use of tablets, injections and drops of haloperidol.

Strictly forbidden to use :

1. With in advance of the depressed central nervous system with high toxicity.
2. Strictly is contraindicated in children of before reaching the age of three.
3. It is also not recommended to use the drug for people who have an increased sensitivity to butyrofenone and its derivative, since severe allergic reactions will occur.
4. Similarly, it can not be used by to people with an allergy to lactose , since the drug contains a high percentage of milk sugar.

Can be used, but with caution

There are cases where the drug Haloperidol can be used, but given the condition of the patient:

1. The drug also applies when removing hiccups, emetic state of that were caused by the use of antitumor therapy, but not eradicatedcompletely. However, only a qualified doctor can prescribe a dose.
2. With particular care, should be used for cardiovascular diseases .As there can be serious consequences, and even a lethal outcome.
3. In kidney or liver diseases in severe forms, the drug is also acceptable, but undesirable.

Mechanism of action

Haloperidol is involved in blocking the receptors of central dopamine and in the receptors of the limbic and mesocortical brain structure. This way of blocking leads to the fact that the production of prolactin increases, which provokes a decrease in temperature.

Thus, the dopamine receptors are completely blocked and a complete antiemetic effect is achieved.

Instructions for Use

The instructions for use for haloperidol deanate, ratopharm and other forms of the drug are almost identical.

The course of treatment can reach a duration of a couple of months. If there is an improvement, the dose of the drug is reduced. For children whose weight reaches less than 40 kilograms, the daily dosage should not exceed 0.15 milligrams.

How to use

The drug is used internally for half an hour before eating. In order to reduce the irritant effect of the drug on the slime , milk is used.

Dosages of Haloperidol

If Haloperidol is used as an antiemetic drug , then it is taken for a half milligram.

For the elderly, is the norm of one third of the dose for adults.

It rises to one second every two days.

Forms of release

The drug is available in the form of tablets, a drop and a solution, placed in transparent or translucent ampoules.

Overdose and additional indications

If an overdose of the drug occurs, it is accompanied by an increase in body temperature.

If the overdose was serious, then the reaction of the organism of a more serious property is possible: from convulsions to coma.

Side-effect of

The instructions for use indicate that drops, tablets and injections of haloperidol have side effects.

The list is quite voluminous: is dyspepsia, and vomiting and headache. It is not rare cases of attacks of euphoria, fear, an overabundance of feelings, excessive euphoria.

Symptoms of , such as decreased appetite, weight, urinary retention, impairment of menstruation, edema, fuzzy vision, allergy also occur.

A serious side effect is also jaundice, however, these are isolated cases.

Special instructions

In case of an overdose, it is recommended to use activated charcoal. It is strictly forbidden to apply the drug epinephrine, and dialysis will simply be ineffective.

Interaction with other drugs

Since haloperidol is considered to be a serious and powerful drug, it is recommended to use it with various medications with caution .It increases the effect of drugs for anesthesia, hypnotics.

Along with the drugs that are used to treat Parkinson's disease, it is not recommended to use haloperidol, as it will reduce their effectiveness.

The same with drugs for the treatment of cramps. If the drug is taken with bupropion, then epilepsy may occur. Too strong tea or coffee can also reduce the effect of taking haloperidol.

In pregnancy and lactation

Since haloperidol reliably penetrates into breast milk, use during pregnancy and subsequent breastfeeding is strictly prohibited.

Reviews of patients and doctors

Reviews of people about Haloperidol are basically positive, we'll see what doctors and patients say.

Reviews of doctors

Comments of doctors indicate that haloperidol is best used in emergency cases:

1. "I recommend using haloperidol only in critical cases, since the drug is very powerful. The most important thing is not to self-medicate, but in time to see a doctor. "( Konstantinov RA)
2. "Haloperidol is an excellent remedy that is widely used in medicine. The drug has many side effects, but with proper application and observance of all recommendations, there should not be any difficulties with its use ".( Savelyev SU)

Patient feedback

And at this time patients say the following:

1. " I am absolutelydid not like this medicine. Its composition is solid chemistry. Only to poison yourself and children. Do not buy it! Buy better something natural! "( Nina)
2. " A good tool that we bought grandfather, and which coped well! But the side effects in the form of bouts of dyspepsia were. .. But it quickly passed! »( Vera Nikolaevna)

Pros and cons of reviews and practical experience of using

We can highlight such advantages of the drug as reasonable price and high quality of , but a large listlimitations in use and side effects significantly spoils the whole picture.

Release forms and cost

Price for Haloperidol( Biocom) tablets 15 rubles .Haloperidol( Ozone) - 20 rubles .Haloperidol-acry costs 25 rubles, and haloperidol-forte - 57 rubles .The price for haloperidol drops drops in the redistribution of 50 rubles.

Conditions and shelf life of

The drug is stored in complete isolation from the sun. Storage temperature should not exceed 30 degrees. Desirable temperature - from 15 to 20 degrees Celsius.

The drug can be used for 5 years from the date of manufacture specified on the package.

Leave at pharmacy

Haloperidol is available on prescription by a specialist doctor.

Analogues of the preparation

In medical practice, various analogues of Haloperidol are widely used. The most are popular Leponex, Mazeptil and Imovan.

Leponex

The drug contains silicic acid, polyvinylpyrrolidone and clozaline. Produced in the form of tablets.

The drug is effective due to the antipsychopathic effect that it has on the body.

Remarkably, copes with both productive and negative types of schizophrenia .Studies have shown that, if the drug is taken for a long time, the symptoms of schizophrenic disorders disappear virtually without a trace.

Leponex is prescribed only by a doctor who selects a dose depending on the form and neglect of the disease. Also, the use of the drug in practice has shown positive results in reducing the risk of suicidal tendencies in patients.

Mazeptil

Also available as tablets. The drug has inhibitory effect on the central nervous system , causing a calming but not hypnotic effect.

It is used in the treatment of behavior, which is characterized by frequent changes in motor activity: the person becomes stunned, then seizures envelop him. But the drug can not be used for organic diseases of the nervous system.

Imovan

Unlike Mazepril, has a hypnotic effect on the body. Also it excellently prevents seizures. The agent is quickly excreted from the body, and the absence of weakness after sleep shows the effectiveness of the drug.

However, the remedy can not be used for sleeping problems, since it can negatively affect the nervous system.

It is not recommended to use it even with frequent nocturnal awakenings.

The drug is taken as sedative before going to bed, but it can cause a number of side effects: vomiting, rashes, dizziness, etc. Imovan, like all analogs of Haloperidol, is strictly forbidden to use while waiting for the child and the subsequent stage of feeding!