MCHC in a blood test. What is it, promoted, demoted, norm and deviation in a child, pregnant women. What to do

ICSU - an important indicator in the overall analysis of the blood, which reflects the qualitative composition of biological fluid that fills the human vessels. He is classified as a red blood cell indices. ICSU level allows to quickly diagnose dangerous diseases such as anemia, cancerous processes in bone marrow, viral liver disease, hypothyroidism thyroid.

What does the figure MCHC in a blood test?

ICSU blood test - is the average concentration of hemoglobin contained in red blood cells. Analysis reflects the degree of saturation of blood cells with protein compounds.

Reduced ICSU indicator is an alarm signal, indicating the possible presence of diseases breaking hemoglobin synthesis in the body. For laboratory research is not used whole blood and isolated it from the packed red blood cells.

Role mchc indicator in the diagnosis of diseases

ICSU in the blood analysis - a biological indicator, which gives an opportunity to evaluate the activity erythrocytes and their hemoglobin saturation, and the body's ability to consume enough oxygen.

Any deviation of the concentration mchc performance standards is to hold additional straight base examination of the patient to determine concomitant diseases of endocrine glands, liver, blood. In adults who do not have internal organs pathologies receiving a balanced diet, the concentration of mchc is always in the normal range.

types of indexes

Also qualitative blood parameters as MCHC levels, erythrocyte indices are the following, which also represent the concentration of hemoglobin in intracellular space:

• MSV - shows the average volume of red blood cells (in lab conclusion displayed in cubic micrometers, or in the femtolitrah);
• SIT - medium level of hemoglobin is not contained in the total erythrocytic mass, and in each test cage individually.

Together with the above indices MCHC indicated in the results of a clinical blood test to doctor conducting the examination of the patient, had an idea of ​​the functionality of the cell species.

Differences between MCHC and MCH

ICSU blood test - a measure of hemoglobin, which displays the data on the average level of hemoglobin in the red blood cell mass. MCH level gives more information about the qualitative composition of the blood, as a specialist, conducting analysis, establishes the average amount of hemoglobin in each red blood cell. This is the key difference between the indices MCHC and MCH.

Norm for men, women, children

Like most other blood components, the level of ICSU in many respects depends on the person's age and gender. Below is a table which shows the average concentration of hemoglobin in the norm of the composition of red blood cell mass.

physiological characteristics	ICSU norm
Children under 5 years	From the first days of birth and before the age of 5 years, average rates which ranges from 280 to 350 g / l
Child from 6 to 12 years	Is maintained within 370 g / l
Adolescents (13-17 years)	In connection with the beginning of puberty in boys ICSU rate increases to 380 g / l, and girls is slightly reduced, making 360 g / l
Men from 18 to 45 years old	Averages norm - 330-360 g / l
Women from 18 to 45 years old	Slightly lower than in young men and constitute 320-350 g / l

The difference in the level of ICSU in girls and boys of adolescence as well as in mature men and women, due to the specific hormonal levels and the presence of a monthly blood loss in women representatives floor.

Once adults reach the age of 45 years, there is a natural slowing down of all biochemical processes in the body. The division of blood cells also occurs not so intense, so the rate of the average concentration of hemoglobin in the red blood cell mass falls to 10-20 g / l.

Indications for analysis MCHC

ICSU blood test - an indicator of the overall health of the body.

The presence of these symptoms is a direct cause for this analysis:

• hard breath;
• shortness of breath that occurs after physical exertion small;
• discoloration of feces on the background of the normal operation of the digestive system;
• increase in spleen tissue;
• rapid pulse;
• irregular heartbeat;
• constantly low blood pressure;
• chronic fatigue, fainting, dizziness;
• yellowing of the whites of the eyes;
• pale skin;
• muscle weakness.

These symptoms of a disease state characterized by the body for many diseases of internal organs. Despite it all, they also may arise at deficiency of hemoglobin in the red blood cell composition. Having the initial examination of the patient by the attending physician prescribes general blood analysis change, the results of which is set concentration MCHC.

Preparing and conducting research

ICSU blood test - an indicator, the definition of which requires the patient to the strict observance of several rules.

they are as following:

• 1-2 days prior to the survey from the diet completely excluded meals containing fat, marinated, smoked foods, and alcohol;
• donate blood only on an empty stomach, and before its intake does not eat for the last 8 hours;
• the evening before the diagnosis is necessary to have supper light salad of fresh vegetables or lean porridge, prepared from cereals, but do not overeat (wheat, barley, barley, corn, oat croup);
• 1 hour prior to blood donation is forbidden to smoke and to take vicarious preparations containing in its structure nicotine.

For analysis using capillary blood which is taken from the beams of the ring finger of the upper limb. Men and women professionally engaged in sports, you must stop the exercise at least 3 days before delivery of a biological material.

Females should take into account the fact that the diagnosis should be conducted not earlier than after 5 days from the completion of menses.

How to wait for analysis results

At the clinics, laboratories which have advanced medical equipment, is often used automatic analyzers ICSU level in erythrocyte mass. It takes 15 to 30 minutes.

If the health facility does not use such methods for determining hemoglobin, the laboratory performed the identification of ICSU with a microscope. In carrying out this diagnostic method will need a 2 to 6 hours. Much depends on the level of professionalism and experience of a specialist.

How is the index

In the process of studying a medical capillary blood conducting its investigation, determines the amount of the protein hemoglobin compounds, pointing it in the laboratory prison.If automatic analyzer, ICSU weight is displayed on a computer monitor, together with those of other blood components. The calculation is in grams. 1 l of blood.

deciphering responses

Decryption process research results collected blood for ICSU concentrations in erythrocyte mass is to conduct a comparative analysis. If the results are higher or lower than the norms specified in the table, it is a chance to pass the patient a more thorough diagnostic examination.

if an error is possible in the analysis mchc

ICSU blood test - an indicator, the results of which can be distorted under the following conditions and factors:

• not complied with the rules of preparation for analysis;
• technician performing the diagnostics erred in determining the average weight of hemoglobin;
• equipment used for the automatic analysis of blood, does not work properly;
• the patient was taking medications that are capable of altering the biochemical composition of the blood.

Probability of the false data, after analysis on MCHC level does not exceed 3%. At the slightest suspicion of error doctor may recommend a patient to be examined again.

When the need for more research

Performing diagnostic re RBC for the average concentration of the protein hemoglobin compounds may require in the following cases:

• the results of the initial survey found disease in violation of ICSU level, the patient runs a course of therapy that requires constant monitoring of the amount of hemoglobin;
• the first study of the biological material was carried out with violations;
• the patient does not follow the rules of preparation before delivery capillary blood;
• a detailed examination of the body is not given the opportunity to determine the cause of disorders of hemoglobin standards, as well as set the current disease of the blood or internal organs.

Additional studies of the biological material to identify entirely ICSU level are held very rarely. In most cases, full blood count indicators give your doctor detailed information about the state of health of the patient.

The reasons for increased rates of symptoms

Increasing the concentration of hemoglobin in the blood erythrocyte mass causes pathological states of the organism. Most often, they are expressed in the diseases listed below.

Anemia. Types of anemia affecting the index mchc

Among the pathologies of the blood, which could cause ICSU indicators are the following types of anemia:

• hyperchromic - cluttering erythrocytes hemoglobin, making them short life and causes premature cell death;
• megaloblastnaya - shaped red blood cells is too large, the presence of which stimulates the body to synthesize large amounts of hemoglobin.

  

In this case, the patient experiences dizziness, muscle weakness, possible heart rhythm disturbances, heart rate quickens reduction. For this category of patients characterized by a sudden loss of consciousness.

liver disease

The main body of the pathology, which is capable of synthesis disrupt erythrocytes and hemoglobin protein compounds is hepatitis. He may have a viral etiology or intoxication.

The patient experiences severe pain in the right upper quadrant, feeling a bitter taste in the mouth, physical weakness, loses appetite, suffocated after the slightest physical exertion. The skin becomes pale with a waxy sheen. Color whites of the eyes varies from white to yellow. In severe cases there may be a complete discoloration of feces.

Oncology

In the presence of blood cancer observed violation of the norms of ICSU and the MNF in excess of the performance of a few dozen times. This is due to the fact that under the influence of degenerated cells of the bone marrow starts to produce a greater number of red blood cells, which are filled with excess weight hemoglobin.

The patient loses weight rapidly, feel physically weak, often loses consciousness, he observed decrease in blood pressure, joins shortness of breath, pain in the long bones.

hypothyroidism

Thyroid disorder characterized by decreased production of thyroid hormone. Deficiency of this biochemical substances entails impaired bone marrow function. As in the case of cancer lesions of blood, causing excessive synthesis of erythrocytes and hemoglobin. Stabilization of hormonal levels can restore the optimal composition of the blood.

The dangerous increase in performance analysis

The major danger of high concentration ICSU erythrocyte mass is that cells supersaturated protein compounds hemoglobin, are not able to fully implement its the transport function.

Most of the red blood cells die even before it reaches the tissue of internal organs, providing them with the necessary amount of oxygen. The result of this is the development of systemic dysfunction accompanying diseases associated with disruption of the heart, liver, kidney, lung.

Correction performance drugs

Stabilization ICSU level is possible by receiving drugs with properties and blood thinners reduce the concentration of its cells, namely:

• trental;
• chimes;
• Acetylsalicylic acid;
• Cardiomagnil.

The dosage and duration of admission is determined individually by the attending physician based on the results of the clinical analysis of capillary blood. Self therapy can provoke deterioration of general health.

diet therapy

To hemoglobin in the red cell indices of blood were within normal limits, pIt is recommended to use the following types of food to eat:

• bananas;
• freshwater fish;
• vegetables and herbs;
• cottage cheese;
• all kinds of fresh fruit;
• vegetable soups;
• apricots;
• cereal porridge;
• chicken meat;
• bananas;
• yogurt, low-fat sour cream, yogurt, fermented baked milk;
• sauerkraut;
• all kinds of legumes.

The principle dietary elevated levels of ICSU is that all dishes are light, quickly absorbed by the digestive system, do not create additional burden on the liver, but at the same time provide the body with a sufficient amount of protein, carbohydrates, fats, vitamins and minerals.

The reasons for lowering the index, symptoms

The decrease in the level of hemoglobin in the red cell blood is no less dangerous than maintaining its high performance. This pathology may arise due to the following reasons.

Low levels of iron in the blood

In order to ensure all functions of blood in the human body should not be less than 5 mg of iron. Permanent lack of this mineral leads to iron deficiency anemia.

Reduced levels of erythrocytes and hemoglobin concentration falls correspondingly. The patient feels dizzy, complains about the lack of air, headaches, lower blood pressure, can not concentrate. Most of the time the patient spends in bed, so physically very weak.

Hereditary blood disease

One of the most common inherited blood disease is thalassemia. Availability of this disease involves a violation of the process of constructing protein chains within cells.

Hemoglobin, which goes inside red blood cells, is not able to fully fill in the intracellular space. In connection with the patient find the exact same symptoms, as well as in iron deficiency anemia. To determine the genetic disorder requires a more thorough examination of the patient.

Deficiency of vitamin B6

Normal concentration of vitamin B6 in humans - is 2 mg. The disadvantage of this substance leads to impaired conversion of polypeptide bonds hemoglobin. The patient noted shortness of breath, rapid heartbeat, tachycardia, low blood pressure, paleness of the skin.

The dangerous drop in performance analysis

It is thought that too low MCHC indices are more dangerous to health than the excess of the established norm. This is due to the fact that in terms of hemoglobin deficiency develops oxygen starvation of cells that form the basis of the internal organs tissues.

You may experience atrophy of the heart muscle, reduced lung volume, cerebral atherosclerosis. Lowering of MCHC is especially dangerous for adolescents which organism is under active form, as well as pregnant women. In the latter case it is not excluded fetal hypoxia and abnormalities of fetal development.

Formulations for normalizing low ICSU

To increase the level ICSU use medicaments containing in its composition the compound 2 and 3-valent iron.

The following are considered the most effective drugs:

• Aktiferin;
• Ferretab;
• Feropleks;
• tardiferon;
• Fenyuls;
• Sorbifer.

Before the start of drug therapy is necessary to pass a comprehensive examination and establish the cause, which caused a decrease in hemoglobin in the red blood cell mass. This will allow to pick the optimal dosage and to determine the duration of treatment.

diet therapy

Proper organization of diet combined with drug therapy, to speed up the process of recovery of the patient and stabilize the performance of ICSU.

It is recommended to saturate your diet the following foods and beverages:

• pepper;
• all kinds of citrus fruit;
• Ocean Fish;
• seafood;
• tomatoes;
• beef, pork, rabbit meat, turkey, nutria;
• Cod liver;
• cauliflower;
• walnuts;
• buckwheat;
• peanut;
• pork liver, kidneys, lungs, heart;
• broth hips;
• beetroot.

A distinctive feature of the diet therapy, aimed at ICSU increase in blood analysis, is that the use of the above products - is not only useful but also delicious. After treatment, medication therapy and correction of the diet need to pass the capillary blood again to have the data on the effectiveness of the passed course of therapy.

Registration of the article: Mila Friedan

Video of ICSU in a blood test

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