Diprospan remedy for joint pains for adults, children, pregnant women. Instructions for use, reviews, price, analogs

Diprospan - a glucocorticosteroid remedy for joint pain. It is a liquid with no color or light yellow shade. After loosening the counter is a mixture.

Why do I need Diprospan

Diprospan prescribed for:

• brain edema;
• diseases of the bones, muscles, soft tissues;
• rheumatoid arthritis;
• fascia;
• ankylosing spondylitis;
• osteoarthritis.

Helps Diprospan at different forms of allergy, including bronchial asthma type, rhinitis (seasonal or permanent) pollinosis.

Composition means

Diprospan - a means of pain joints, consisting of a basic substance - betamethasone disodium phosphate. This is a chemical compound that dissolves easily and quickly absorbent cloth after the breakup and removal. The second substance - betamethasone dipropionate having at excretion rate.

The combined effects of these substances has a dual scale: the action can be fast or delayed.

Efficiency levers does not change regardless of the route of administration, which may be:

• intraarticular;
• intravenous;
• subcutaneous;
• intramuscular.

issuance

The medicine is available in a 1 ml ampoule. The medical tool can be equipped with a syringe and needle.

pharmacodynamics

Diprospan belongs to a group of corticosteroids and a remedy for pain joints. It has glucocorticoid activity, positive effect in inflammation, certain allergy symptoms.

Once in the body, the active component diprospana begins to interact with cytoplasmic receptors. As a result, a complex is formed, penetrating into the cell nucleus and stimulate production of messenger RNA, which promotes the production of proteins - such as Lipokortin.

Diprospan affects the following metabolic processes in the human body:

exchange views	Description
proteinaceous	Due globulins in blood becomes less protein, thus accelerating the formation of albumin in the kidney and liver
lipidic	Accelerating the production of fatty acids, there is a redistribution of fat, developing hypercholesterolemia
carbohydrate	Increasing the amount of intake of carbohydrates from the intestine, increasing activity of glucose-6-phosphatase
Water-electronic	The body of water is retained longer and sodium ions, is reduced intake of calcium from the intestine

Diprospan may also have the following effects:

1. Anti-inflammatory. It is based on the formation of lipokartina. The drug reduces the number of mast cells and capillary transmittance, stabilizes the cell membrane.
2. Antiallergic. The drug inhibits the release of histamine, inhibits antibody production, alters the immune response.
3. Immunosuppressive. This impact is caused by a decrease in the rate of release of cytokines. The drug affects the connective tissue reactions occurring in inflammation.

Pharmacokinetics

Main Diprospan active substance is dissolved in water, so after its administration by intramuscular injection, immediately begin the hydrolysis: the substance is rapidly absorbed from the site where it was injected.

Therapeutic effect will not have to wait long: 24 hours after ingestion of betamethasone it is almost completely removed from the body. Active ingredient means capable of connecting to plasma proteins. Excreted by the kidneys.

application

Dosage and method Diprospan revenues depend on the type and severity of the disease.

Apply the medicine prescribed by 3 ways:

1. intramuscularly (With regular admission means). It is best to chop at an angle of 90 degrees into the muscles in the upper square buttocks. The maximum single dose must be not less than 0.2 ml / cm², weekly - 1 ml. Before the introduction of the drug should be heated to 16-17 ° C.
2. Intra-articularly. Applicable only in the clinic. The procedure can be carried out only by a specialist, self - is unacceptable. Usually painless introduction means, if desired, the anesthetic can be connected.
3. Intralesional (E.g., arthritis). Prick accompanied by pain. Make yourself at home is prohibited, or possibly loss of consciousness and deterioration.

Individual appointments depending on the evidence, the complexity of the disease and the patient's reactions.

It is important to adhere to the following guidelines:

1. If the course lasts more than 5 days, the daily dose should not exceed 2 ml. It is introduced intermittently, if after a long therapy will not be expected effect, the treatment is terminated or replaced by another means.
2. At maturity of anaphylactic shock, a shot is 1 times.
3. Independently carried out an injection is performed only intramuscularly.
4. Intravenous means not applicable.
5. Shot in the nose can be made to carry out only in a hospital.

The active effect of the drug begins 10 minutes after the injection, the duration of exposure - about 72 hours. If the patient's condition is not critical, to prick it is necessary to pass a complete blood count and sugar content of more research - the number of phage and white blood cell count.

For children up to 18 years

Children who received treatment diprospanom must often examined by pediatricians. This is especially true in cases where treatment is long. Doctors should monitor the growth of the child and the lack of adrenal insufficiency. If it is found, or the child began to rise slowed, therapy should be stopped.

adult

Preparing a suspension in a mixture of 1% sodium chloride and glucose. After connection of the components necessary to enter the resulting solution. If after the administration remains a certain amount of solution, it is possible to put the remainder in the refrigerator and keep it there. However, it should be remembered that the period of storage in this case does not exceed 24 hours. On the first day after the beginning of storage residue slurry to be applied.

No smoking mix original agent with the solution of some analgesic drugs, such as procaine or lidocaine. Mix the substances it is necessary in the syringe, not in the bottle. Before starting therapy with steroid drugs, you need to identify indicators of blood substance. Also, watch out for these indicators after the start of therapy.

For pregnant

Given that safety studies Diprospan during pregnancy was not, it is valid in a situation where the expected result after receiving the higher risk of exposure to the fetus. Betamethasone can flow through the placenta and inhibit development of the child. With long-term and repeated use of corticosteroids may increase the risk of developing and vynashivaemosti child.

for elderly

Diprospan (by means of joint pain) can not be used for older patients who have heart problems or chronic diseases of the respiratory system.

Contraindications

Means is contraindicated in:

• hypersensitivity (can not be administered parenterally);
• joint infection, and blood clotting difficulties with (you can not enter intra-articular);
• various skin diseases, as well as viral and bacterial infections (not allowed to apply topically).

Impermissible means:

• those with high sensitivity to main (betamethasone) and additional components included in the composition;
• in mycosis;
• children who are under 3 years old due to the presence in the composition of alcohol adversely affects the child's body.

You can not drive both immunosuppressive doses Diprospan and live attenuated vaccines.

Overdose

If the patient does not comply with the rules and introduce more than the recommended dose, then it will appear the following symptoms:

• high excitability;
• nausea;
• vomiting;
• depression;
• euphoria;
• insomnia.

In applying the drug over a long time is high possibility to encounter problems such as:

• osteoporosis;
• swelling;
• breach of the functioning of the adrenal glands.

Severe overdose can lead to life-threatening situation. No consequences would not be, if we use small doses.

To avoid the negative effects of this medication overdose should do the following:

1. Call an ambulance or go to the hospital. The doctor should monitor the patient's condition and do everything possible to prevent it getting worse.
2. Monitor the patient's behavior.
3. Provide patient and abundant drink plenty of water.
4. Monitor the amount found in the blood and urine electrolytes. Most of all it concerns the potassium and sodium ions.

If the need arises, you will need to hold the appropriate treatment.

Side effects

Diprospan - means of joint pains, which has side effects such as:

• depression;
• disturbed sleep;
• hyperexcitability;
• frequent neurosis;
• anxiety disorder;
• maldigestion;
• polyphagia;
• growth of body weight, which is caused by disturbed metabolism;
• osteoporosis;
• inhibition of growth in children;
• complication of infections;
• swelling;
• deterioration in people with diabetes.

drug interactions

When used together with other medicines Diprospan may be some effect.

In particular, if Diprospan combine with:

• phenobarbital, phenytoin or ephedrine, the patient may accelerate metabolism of betamethasone and its therapeutic effect is reduced;
• indirect anticoagulants, can change the blood clotting;
• diuretics, leading out potassium, significantly increases the likelihood of the emergence and development of hypokalemia;
• amphotericin B, accelerated excretion of potassium organism;
• cardiac glycosides, it will significantly increase the risk of arrhythmia;
• growth hormone, slows the absorption of the latter.

Necessarily need to adjust the dose when using corticosteroids and estrogens otherwise there is a great danger both groups overdose. It should be remembered that the SCS may affect one of the tests by which to detect the presence of bacterial infection. So, the result of nitrogen blue tetrazolevogo test may be false.

Studies show that Diprospan affect the action of insulin and all the preparations which are intended to reduce the sugar content and lower blood pressure. Assigning his patient Diprospan, the doctor must remember that its constituent material adverse effect on the action of diuretic components of vaccines.

Nuances in the use of the drug as follows:

• the exclusion of alcoholic beverages;
• in alcoholic intoxication gastric lavage;
• exception of combining it with other toxic agents.

Conditions and terms

Keep the drug is necessary in places where can not reach small children. The room temperature may not exceed + 25 ° C and below + 2 ° C. Location should be chosen reliably protected from direct sunlight.

In this case, the medicament is suitable for use for 2 years from date of manufacture. If the package will be found any damage, the product must be disposed of immediately.

Conditions of supply of pharmacies Diprospan

Diprospan manufactured strictly according to the prescription of a doctor.

analogs diprospan

In pharmacies can purchase drugs that the composition and effects of virtually identical diprospanom.

This may include the following ointment or cream:

1. Belderm. Apply a thin layer of the first time - 2-6 times per day, then - 1-2 times. Children are not recommended to use means more than 5 days.
2. Kuterid. The ointment is applied morning and evening, prophylactically - 1 time only.
3. Akriderm. Is applied to the affected area 1-3 times per day. The course - a maximum of 3 weeks. Children under 12 years old remedy applies under the supervision of a specialist.
4. Betliben. It is intended in the treatment of dermatitis, vetiligo, psoriasis, itching, weeping particularly effective in forms and oily skin. Apply a thin layer, and is easy to rubbing 1-2 times a day. The maximum rate - 3 weeks.

Analogs of jabs considered Tseleston and Flosteron. Diprospan - a remedy for pain of the joints, which also affects the metabolism. The main thing is to comply with dosage and remember about the side effects.

Videos about Diprospan preparation, its efficiency and application rules

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